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EsxH Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)

(Synonyms: Protein TB10.4, Low molecular weight protein antigen 7, esxH, ESAT-6-like protein EsxH, cfp7, 10 kDa antigen CFP7 (CFP-7)) Copy Product Info

Synonyms: Protein TB10.4, Low molecular weight protein antigen 7, esxH, ESAT-6-like protein EsxH, cfp7, 10 kDa antigen CFP7 (CFP-7)

Catalog No. TMPH-03011 Copy Product Info
EsxH, in complex with EsxG, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS), a component of the ESCRT machinery.
EsxH Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$12920 days20 days
10 µg$21620 days20 days
20 µg$36020 days20 days
50 µg$54320 days20 days
100 µg$74520 days20 days
200 µg$1,07020 days20 days
500 µg$1,73020 days20 days
1 mg$2,53020 days20 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
EsxH, in complex with EsxG, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS), a component of the ESCRT machinery.
Species
Mycobacterium tuberculosis
Expression System
E. coli
TagN-6xHis-SUMO
Accession NumberP9WNK2
Amino AcidSQIMYNYPAMLGHAGDMAGYAGTLQSLGAEIAVEQAALQSAWQGDTGITYQAWQAQWNQAMEDLVRAYHAMSSTHEANTMAMMARDTAEAAKWGG
Construction2-96 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsProtein TB10.4, Low molecular weight protein antigen 7, esxH, ESAT-6-like protein EsxH, cfp7, 10 kDa antigen CFP7 (CFP-7)
Research Background
EsxH, in complex with EsxG, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS), a component of the ESCRT machinery.
Chemical Properties
Molecular Weight26.3 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: EsxH Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO) chemical structure | EsxH Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO) molecular weight