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Pheleuin

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Catalog No. T36854Cas No. 169195-23-7

Pheleuin is a pyrazinone derivative synthesized from a dipeptide aldehyde. Although the biological activity of this compound has not been reported, similar diketopiperazines are known to inhibit calpain and/or regulate S. aureus virulence factor expression.

Pheleuin

Pheleuin

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Catalog No. T36854Cas No. 169195-23-7
Pheleuin is a pyrazinone derivative synthesized from a dipeptide aldehyde. Although the biological activity of this compound has not been reported, similar diketopiperazines are known to inhibit calpain and/or regulate S. aureus virulence factor expression.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$22335 days35 days
5 mg$97835 days35 days
10 mg$1,72035 days35 days
25 mg$3,77035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
Pheleuin is a pyrazinone derivative synthesized from a dipeptide aldehyde. Although the biological activity of this compound has not been reported, similar diketopiperazines are known to inhibit calpain and/or regulate S. aureus virulence factor expression.
Chemical Properties
Molecular Weight242.32
FormulaC15H18N2O
Cas No.169195-23-7
SmilesO=C1NC(=CN=C1CC(C)C)CC=2C=CC=CC2
Relative Density.1.09 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 5 mg/mL (20.63 mM), Sonication is recommended.
DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL (2.06 mM), Sonication is recommended.
DMSO: 20 mg/mL (82.54 mM), Sonication is recommended.
DMF: 20 mg/mL (82.54 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO/DMF
1mg5mg10mg50mg
5 mM0.8254 mL4.1268 mL8.2535 mL41.2677 mL
10 mM0.4127 mL2.0634 mL4.1268 mL20.6339 mL
20 mM0.2063 mL1.0317 mL2.0634 mL10.3169 mL
DMSO/DMF
1mg5mg10mg50mg
50 mM0.0825 mL0.4127 mL0.8254 mL4.1268 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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