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Anti-ENPP7 Antibody (6N785) is a Rabbit antibody targeting ENPP7. Anti-ENPP7 Antibody (6N785) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $268 | 7-10 days | 7-10 days |
| Description | Anti-ENPP7 Antibody (6N785) is a Rabbit antibody targeting ENPP7. Anti-ENPP7 Antibody (6N785) can be used in ELISA. |
| Synonyms | Gm254, ectonucleotide pyrophosphatase/phosphodiesterase 7, Alk-SMase |
| Ig Type | Rabbit IgG |
| Clone | 6N785 |
| Reactivity | Human |
| Specificity | Human ENPP7 |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ENPP7 / NPP-7 (rh ENPP7; TMPY-01070; NP_848638.2; Met 1-Ser 439). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Ectonucleotide pyrophosphatase / phosphodiesterase family member 7, also known as Alkaline sphingomyelin phosphodiesterase, Intestinal alkaline sphingomyelinase, Alk-Smase, ENPP7 and NPP-7, is a single-pass type I membrane protein which belongs to thenucleotide pyrophosphatase / phosphodiesterase family. ENPP7 / NPP-7 is expressed in the intestines and human bile. ENPP7 / NPP-7 is localized at the surface of the microvillar membrane in small intestine enterocytes, as well as in endosome-like structures and in Golgi complex. The main function of ENPP7 / NPP-7 is to convert the dietary sphingomyelin into ceramide, the sphingolipid messengers via hydrolyzation. ENPP7 / NPP-7 is also reported to exert a phospholipase C activity toward palmitoyl lyso-phosphocholine. The activity of this enzyme is inhibited in a dose dependent manner by ATP, imidazole, orthovanadate and zinc ion. Further, It has been shown in studies that decreased levels of ENPP7 / NPP-7 may be associated with human colon cancer. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ENPP7 protein (TMPY-01070) |
| Antigen Species | Human |
| Biology Area | Phosphatases and Regulators |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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