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Anti-THAP1 Antibody (8N883)
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Catalog No. TMAC-04027
Alias THAP1_HUMAN, THAP domain-containing protein 1, THAP domain protein 1, THAP domain containing protein 1, THAP domain containing apoptosis associated protein 1, THAP domain containing 1, THAP 1, Thap 1, Nuclear proapoptotic factor, MGC33014, FLJ10477, DYT6, 4833431A01Rik
Anti-THAP1 Antibody (8N883) is a Mouse antibody targeting THAP1. Anti-THAP1 Antibody (8N883) can be used in WB,ICC,FCM.
Anti-THAP1 Antibody (8N883)
Anti-THAP1 Antibody (8N883)
😃Good
Catalog No. TMAC-04027Alias THAP1_HUMAN, THAP domain-containing protein 1, THAP domain protein 1, THAP domain containing protein 1, THAP domain containing apoptosis associated protein 1, THAP domain containing 1, THAP 1, Thap 1, Nuclear proapoptotic factor, MGC33014, FLJ10477, DYT6, 4833431A01Rik
Anti-THAP1 Antibody (8N883) is a Mouse antibody targeting THAP1. Anti-THAP1 Antibody (8N883) can be used in WB,ICC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $427 | 7-10 days |
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Chemical Properties
| Description | Anti-THAP1 Antibody (8N883) is a Mouse antibody targeting THAP1. Anti-THAP1 Antibody (8N883) can be used in WB,ICC,FCM. |
| Synonyms | THAP1_HUMAN, THAP domain-containing protein 1, THAP domain protein 1, THAP domain containing protein 1, THAP domain containing apoptosis associated protein 1, THAP domain containing 1, THAP 1, Thap 1, Nuclear proapoptotic factor, MGC33014, FLJ10477, DYT6, 4833431A01Rik |
| Clone | 8N883 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of THAP1 on human THAP1 recombinant protein using anti-THAP1 antibody at 1/1,000 dilution. 2. Western blot analysis of THAP1 on HEK293 (1) and THAP1-hIgGFc transfected HEK293 (2) cell lysate using anti-THAP1 antibody at 1/1,000 dilution. 3. ICC staining THAP1 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. Flow cytometric analysis of Jurkat cells with THAP1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC: 1:50-200; FCM: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | THAP1 (THAP domain containing, apoptosis associated protein 1) is a 213 amino acid protein that localizes to the nucleoplasm and contains one THAP-type zinc finger, a conserved DNA-binding domain. Interacting with PAR4, THAP1 functions as a pro-apoptotic protein that acts in a zinc-dependent manner and enhances the likelihood of both TNF- and serum withdrawal-induced apoptosis, possibly playing a role in promyelocytic leukemia. The gene encoding THAP1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 25 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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