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Anti-TROP-2 Antibody-HRP (7D257)

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Catalog No. TMAY-00814H
Alias tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M1S1, GP50, GA733-1, GA7331, EGP-1, EGP1

Anti-TROP-2 Antibody-HRP (7D257) is a HRP-conjugated Mouse antibody targeting TROP-2. Anti-TROP-2 Antibody-HRP (7D257) can be used in ELISA.

Anti-TROP-2 Antibody-HRP (7D257)

Anti-TROP-2 Antibody-HRP (7D257)

😃Good
Catalog No. TMAY-00814HAlias tumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M1S1, GP50, GA733-1, GA7331, EGP-1, EGP1
Anti-TROP-2 Antibody-HRP (7D257) is a HRP-conjugated Mouse antibody targeting TROP-2. Anti-TROP-2 Antibody-HRP (7D257) can be used in ELISA.
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100 μg$294 7-10 days
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Product Introduction

Bioactivity
Description
Anti-TROP-2 Antibody-HRP (7D257) is a HRP-conjugated Mouse antibody targeting TROP-2. Anti-TROP-2 Antibody-HRP (7D257) can be used in ELISA.
Aliastumor-associated calcium signal transducer 2, TROP-2, TROP2, TACD2, M1S1, GP50, GA733-1, GA7331, EGP-1, EGP1
Ig Type
Monoclonal Mouse IgG1
Clone
7D257
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 0.1-1 μg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TROP2 extracellular domain (rh TROP2; TMPY-01262; NP_002344.2; Met 1-Thr 274). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little or no expression of Trop-2 in adult somatic tissue. Because it is a cell surface protein that is selectively expressed in tumor cells, Trop-2 is a potential therapeutic target. The cytoplasmic tail of Trop-2 possesses potential serine and tyrosine phosphorylation sites and a phosphatidyl-inositol binding consensus sequence. Trop-2 transduces an intracellular calcium signal, which are consistent with the hypothesis that it acts as a cell surface receptor and support a search for a physiological ligand. TROP2 encoding by an intronless gene was originally defined by the monoclonal antibody GA733, and is a member of a family of at least two type I membrane proteins. The other known member is GA733-2, also called EpCAM and TROP1. It has been suggested by studies that the GA733-1 gene was formed by the retroposition of the GA733-2 gene via an mRNA intermediate.
Related Conjugates and Formulations
Conjucates
HRP
Others Formats
Unconjugated/Biotin/FITC/PE
Antibody Types Available
5
Antigen Details
Immunogen
Recombinant Human TROP2 protein (TMPY-01262)
Antigen Species
Human
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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