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TargetMol | Compound Library

Human Endogenous Metabolite Compound Library Plus

Catalog No. L2501

Changes in biological status (such as hypoxia, nutrients, drugs) usually cause the perturbations in the concentrations and fluxes of specific endogenous metabolites involved in a number of key disease-related or other specific cellular pathways. Extensive efforts in recent years have been focused on metabolic alterations in cancer, the products of intermediary metabolism has been a topic of considerable research interest. Cancer cells exhibit profound alterations in their metabolism. The quantitative measurement of the dynamic multiparametric metabolites, identification and quantification of intermediary metabolism can better help predict the tumor progress, understand the metabolic pathways and molecular mechanism of carcinogenesis. Current researches mainly focus on energy metabolism targeted compounds, such as nucleotides, amino acids, lipids, saccharide, etc. For example, alterations of cellular lipidomics (choline, phosphatidylcholine, cholesterol, etc.) reported in cancer provides a major opportunity to treat and prevent cancer; alterations of glucose metabolism (abnormal pyruvate, lactate, and isobutyric acid, etc.) in cancer cells, which also have become the hotspots in cancer research and therapeutics by targeting lipid metabolism and glucose metabolism.
TargetMol's collection of 817 endogenous metabolism-related compounds, Human Endogenous Metabolism Compound Library, can be used for research in endogenous metabolism-related diseases and drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2501

Human Endogenous Metabolite Compound Library Plus

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 817 endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening;
  • Effective tool for research in endogenous metabolism-related diseases, exploring the tumorigenesis, and drug discovery;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality.
  • Provide professional plate map design: Ensure that each row and column contains compounds with distinct molecular weights to facilitate multiplexing in mass spectrometry.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Targetmol Compound Libraries
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Library Customization | TargetMol Library Composition

Endogenous Metabolite
Apoptosis
Antibacterial
ROS
Amino Acids and Derivatives
Nucleoside Antimetabolite/Analog
Autophagy
NF-κB
DNA/RNA Synthesis
Antioxidant
Reactive Oxygen Species
Antifungal
iGluR
Caspase
Drug Metabolite
Dehydrogenase
PPAR
Mitochondrial Metabolism
Interleukin
Estrogen/progestogen Receptor
ERK
Ferroptosis
Calcium Channel
GABA Receptor
Liposome
NO Synthase
Parasite
NMDAR
GluR
Akt
Nrf2
TNF
p38 MAPK
HSV
HIV Protease
Estrogen Receptor/ERR
FXR
Glucocorticoid Receptor
Influenza Virus
Potassium Channel
NOD-like Receptor (NLR)
Adenosine Receptor
Virus Protease
Adrenergic Receptor
Aryl Hydrocarbon Receptor
MMP
STAT
5-HT Receptor
Antibiotic
GPCR
ATPase
Chloride channel
Glutathione Peroxidase
Phosphatase
PKA
PARP
TRP/TRPV Channel
Fatty Acid Synthase
COX
GPCR19
Bcl-2 Family
AMPK
Cannabinoid Receptor
AChR
Tyrosinase
Dopamine Receptor
Src
Arginase
P2Y Receptor
Reductase
NADPH
Histamine Receptor
JNK
Mitophagy
Serine Protease
Cysteine Protease
PKC
GlyT
Opioid Receptor
Cytochromes P450
Androgen Receptor
mTOR
TGF-beta/Smad
HDAC
HMG-CoA Reductase
Thyroid hormone receptor(THR)
ROR
PI3K
Histone Demethylase
Progesterone Receptor
CaSR
Wnt/beta-catenin
Liver X Receptor
Amylase
IL Receptor
Cholinesterase (ChE)
CXCR
HCAR
Angiotensin-converting Enzyme (ACE)
glycosidase
OXPHOS
Prostaglandin Receptor
TLR
Sirtuin
IκB/IKK
Beta Amyloid
Retinoid Receptor
Phospholipase
NOD
Ras
AhR
Imidazoline Receptor
Vitamin
PGC-1α
Advanced Glycation End Products
NOS
CAT
Carbonic Anhydrase
Transferase
Monocarboxylate transporter
DHFR
YAP
c-Met/HGFR
LTR
Aconitase
Melatonin Receptor
Galectin
c-Myc
Bcl-6
MRP
HBV
Photosensitizer
Glutaminase
MAO
Topoisomerase
E1/E2/E3 Enzyme
LDL
Raf
MT Receptor
Phosphorylase
Antifection
Hexokinase
PROTAC Linker
DPP-4
JAK
Hedgehog/Smoothened
Bradykinin Receptor
Somatostatin
Lipoxygenase
PANoptosis
CaMK
Lipid
MAPK
Glutathione reductase
Survivin
Antiviral
HSP
SARS-CoV
Trk receptor
Free radical scavengers
Histone Acetyltransferase
CPT
Decarboxylase
cGAS
ASK
Pyroptosis
Neprilysin
GPX
Oxytocin Receptor
PLK
MDM-2/p53
Neurokinin receptor
Sodium Channel
DNA Methyltransferase
Sigma receptor
Thrombin
HIF/HIF Prolyl-Hydroxylase
ROS Kinase
CFTR
p53
Glyoxalase
ADC Linker

Keywords