Human Endogenous Metabolite Compound Library Plus

Catalog No. L2501

Library Compound List Excel SDF

Changes in biological status (such as hypoxia, nutrients, drugs) usually cause the perturbations in the concentrations and fluxes of specific endogenous metabolites involved in a number of key disease-related or other specific cellular pathways. Extensive efforts in recent years have been focused on metabolic alterations in cancer, the products of intermediary metabolism has been a topic of considerable research interest. Cancer cells exhibit profound alterations in their metabolism. The quantitative measurement of the dynamic multiparametric metabolites, identification and quantification of intermediary metabolism can better help predict the tumor progress, understand the metabolic pathways and molecular mechanism of carcinogenesis. Current researches mainly focus on energy metabolism targeted compounds, such as nucleotides, amino acids, lipids, saccharide, etc. For example, alterations of cellular lipidomics (choline, phosphatidylcholine, cholesterol, etc.) reported in cancer provides a major opportunity to treat and prevent cancer; alterations of glucose metabolism (abnormal pyruvate, lactate, and isobutyric acid, etc.) in cancer cells, which also have become the hotspots in cancer research and therapeutics by targeting lipid metabolism and glucose metabolism.

TargetMol’s collection of 1300 endogenous metabolism-related compounds, Human Endogenous Metabolism Compound Library, can be used for research in endogenous metabolism-related diseases and drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

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If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com

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Product Description

A unique collection of 1300 endogenous metabolism-related compounds for research in endogenous metabolism-related diseases and drug screening;
Effective tool for research in endogenous metabolism-related diseases, exploring the tumorigenesis, and drug discovery;
Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
Structurally diverse, medicinally active, and cell permeable;
NMR and HPLC validated to ensure high purity and quality.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..

10. Blood. 2021, 137(11): 1478-1490. 11. Nucleic Acids Research. 2021. 12. Nature Communications. 2023, 14(1): 7574. 13. Advanced Science. 2020, 7(16): 2000925. 14. Angewandte Chemie. 2021. 15. Acta Pharmaceutica Sinica B. 2022. 16. Protein & Cell. 2021, 12(11): 877-888. 17. Bone Research. 2023, 11(1): 54. 18. Pharmacology & Therapeutics. (2021): 107930. 19. Nature Communications. 2021, 12(1): 1-12. 20. Journal of Cell Biology. 2022, 221(5): e202112024.

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Library Composition

Endogenous Metabolite (820)

Apoptosis (113)

Autophagy (80)

Antibacterial (71)

Reactive Oxygen Species (41)

NF-κB (41)

Antifungal (36)

Antioxidant (26)

COX (24)

DNA/RNA Synthesis (23)

P450 (21)

Influenza Virus (20)

PPAR (19)

Antibiotic (18)

HIV Protease (17)

Ferroptosis (17)

Estrogen/progestogen Receptor (15)

ERK (14)

GABA Receptor (13)

Parasite (13)

TNF (12)

Amino Acids and Derivatives (12)

HSV (12)

5-HT Receptor (12)

Estrogen Receptor/ERR (12)

Nucleoside Antimetabolite/Analog (12)

Mitophagy (11)

TRP/TRPV Channel (11)

Caspase (11)

AChR (10)

Akt (9)

NO Synthase (9)

PI3K (9)

Calcium Channel (9)

Dehydrogenase (9)

Beta Amyloid (8)

Prostaglandin Receptor (8)

iGluR (8)

JNK (8)

AMPK (8)

MMP (8)

NMDAR (7)

ROS (7)

Anti-infection (7)

GluR (7)

p38 MAPK (7)

Virus Protease (7)

Potassium Channel (7)

Dopamine Receptor (7)

Nrf2 (7)

PKC (6)

IL Receptor (6)

Phosphatase (6)

Adenosine Receptor (6)

Tyrosinase (6)

Mitochondrial Metabolism (5)

Drug Metabolite (5)

STAT (5)

BCL (5)

Lipoxygenase (5)

Opioid Receptor (5)

Adrenergic Receptor (5)

MAO (5)

AChE (5)

Cannabinoid Receptor (5)

Reductase (5)

GPR (4)

Aryl Hydrocarbon Receptor (4)

Glucocorticoid Receptor (4)

Sirtuin (4)

Proteasome (4)

Interleukin (4)

Antiviral (4)

Thyroid hormone receptor(THR) (4)

Arginase (4)

NOS (4)

PKA (4)

Histamine Receptor (4)

Progesterone Receptor (4)

FXR (4)

PARP (4)

ATPase (4)

Chloride channel (4)

Glucosidase (3)

HIF/HIF Prolyl-Hydroxylase (3)

Platelet aggregation (3)

P-gp (3)

Norepinephrine (3)

Serotonin Transporter (3)

Transferase (3)

AhR (3)

TLR (3)

Microtubule Associated (3)

EGFR (3)

SARS-CoV (3)

HMG-CoA Reductase (3)

TGF-beta/Smad (3)

PDE (3)

Xanthine Oxidase (3)

Topoisomerase (3)

Carbonic Anhydrase (2)

GSK-3 (2)

Androgen Receptor (2)

mTOR (2)

ATP Citrate Lyase (2)

Acyltransferase (2)

MAPK (2)

Glutathione reductase (2)

RAAS (2)

VEGFR (2)

MEK (2)

HIF (2)

Trk receptor (2)

GPCR19 (2)

ROR (2)

Histone Acetyltransferase (2)

Phospholipase (2)

Aromatase (2)

GST (2)

ribosome (2)

HDAC (2)

Melatonin Receptor (2)

P2Y Receptor (2)

CaMK (2)

Wnt/beta-catenin (2)

Glucokinase (2)

HER (2)

p53 (2)

E1/E2/E3 Enzyme (2)

UGT (2)

Imidazoline Receptor (2)

Gamma-secretase (2)

LDL (2)

CDK (2)

MT Receptor (2)

Neurokinin receptor (2)

Serine/threonin kinase (2)

Antifection (2)

Phosphorylase (2)

Fatty Acid Synthase (2)

DNA Methyltransferase (2)

Retinoid Receptor (2)

Bombesin Receptor (2)

Syk (2)

JAK (2)

FAAH (2)

NOD (2)

Monoamine Oxidase (1)

Proton pump (1)

Sodium Channel (1)

Integrin (1)

PDK (1)

CYP19A1 (1)

Oxytocin Receptor (1)

DHFR (1)

CFTR (1)

Thrombin (1)

IRAK (1)

CD38 (1)

Sigma receptor (1)

ROS Kinase (1)

PLK (1)

Transaminase (1)

NOD-like Receptor (NLR) (1)

FGFR (1)

stilbene oxidase (1)

Amylase (1)

Lipase (1)

LTR (1)

HBV (1)

ABC (1)

Epoxide Hydrolase (1)

CaSR (1)

Somatostatin (1)

PTEN (1)

CXCR (1)

Bradykinin Receptor (1)

MRP (1)

GNRH Receptor (1)

Hexokinase (1)

c-Myc (1)

GlyT (1)

Cysteine Protease (1)

P2X Receptor (1)

Liver X Receptor (1)

Fas/FasL (1)

PAFR (1)

Immunology/Inflammation related (1)

Leukotriene Receptor (1)

IAP (1)

cAMP (1)

Epigenetic Reader Domain (1)

Reverse Transcriptase (1)

DYRK (1)

BACE (1)

Carboxypeptidase (1)

IκB/IKK (1)

IFNAR (1)

RSV (1)

Casein Kinase (1)

aconitase (1)

Decarboxylase (1)

transporter (1)

Free radical scavengers (1)

DUB (1)

Aminopeptidase (1)

HSP (1)

NADPH (1)

Histone Demethylase (1)

PGE Synthase (1)

Glutathione Peroxidase (1)

Lipid (1)

SGLT (1)

Telomerase (1)

Hedgehog/Smoothened (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty