Anti-CD80 Polyclonal Antibody 2

Name: Anti-CD80 Polyclonal Antibody 2
Brand: TargetMol
SKU: TMAB-00393
Rating: 4.5 (1 reviews)

(Synonyms: LAB7, CD80 molecule, CD80, CD28LG1, BB1, B7-1, B71, B7.1, B7) Copy Product Info

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Synonyms: LAB7, CD80 molecule, CD80, CD28LG1, BB1, B7-1, B71, B7.1, B7

Catalog No. TMAB-00393 Copy Product Info

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Anti-CD80 Polyclonal Antibody 2 is a Rabbit antibody targeting CD80. Anti-CD80 Polyclonal Antibody 2 can be used in FCM,WB.

Anti-CD80 Polyclonal Antibody 2

Pack Size	Price	USA Stock	Global Stock
50 μL	$220	7-10 days	7-10 days
100 μL	$373	7-10 days	7-10 days
200 μL	$528	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Description	Anti-CD80 Polyclonal Antibody 2 is a Rabbit antibody targeting CD80. Anti-CD80 Polyclonal Antibody 2 can be used in FCM,WB.
Synonyms	LAB7, CD80 molecule, CD80, CD28LG1, BB1, B7-1, B71, B7.1, B7
Ig Type	IgG
Reactivity	Human,Mouse,Rat

Application	FCM WB
Recommended Dose	WB: 1:500-2000; FCM: 2µg/Test
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed on activated B-cells, macrophages and dendritic cells.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.

Antigen Details

Immunogen	KLH conjugated synthetic peptide: rat CD80
Antigen Species	Rat
Gene Name	CD80
Protein Name	T-lymphocyte activation antigen CD80
Biology Area	CD,B Lymphocytic Lineage,Dendritic Cell Lineage,Monocytic Lineage
Function	Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.