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Isepamicin sulfate

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Catalog No. T6549Cas No. 67814-76-0
Alias sch21420) Sulphate, Isepamicine (Isepamycin, Isepamicin Sulphate, Isepacin

Isepamicin sulfate (sch21420) Sulphate) , an aminoglycoside antibacterial with good activity against strains producing type I 6-acetyltransferase, inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit.

Isepamicin sulfate

Isepamicin sulfate

😃Good
Purity: 99.91%
Catalog No. T6549Alias sch21420) Sulphate, Isepamicine (Isepamycin, Isepamicin Sulphate, IsepacinCas No. 67814-76-0
Isepamicin sulfate (sch21420) Sulphate) , an aminoglycoside antibacterial with good activity against strains producing type I 6-acetyltransferase, inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$39In StockIn Stock
10 mg$55In StockIn Stock
25 mg$97In StockIn Stock
50 mg$172In StockIn Stock
100 mg$278In StockIn Stock
500 mg$682-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.91%
Color:White
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Product Introduction

Bioactivity
Description
Isepamicin sulfate (sch21420) Sulphate) , an aminoglycoside antibacterial with good activity against strains producing type I 6-acetyltransferase, inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit.
Targets&IC50
30S ribosomal subunit (bacterial):
In vitro
Isepamicin might be active in vitro against Gram-negative bacteria with resistance to amikacin and other aminoglycosides. The antibacterial spectrum of Isepamicin Sulphate includes Enterobacteriaceae and staphylococci, anaerobes, neisseriaceae and streptococci are resistant.
Synonymssch21420) Sulphate, Isepamicine (Isepamycin, Isepamicin Sulphate, Isepacin
Chemical Properties
Molecular Weight667.68
FormulaC22H43N5O12·SH2O4
Cas No.67814-76-0
SmilesOS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@@H](C[C@H](N)C(O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)NC(=O)[C@@H](O)CN)OC[C@]1(C)O
Relative Density.1.53g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 10 mM, Sonication is recommended.
DMSO: Insoluble
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.4977 mL7.4886 mL14.9772 mL74.8862 mL
5 mM0.2995 mL1.4977 mL2.9954 mL14.9772 mL
10 mM0.1498 mL0.7489 mL1.4977 mL7.4886 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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