Anti-IL-1 beta Polyclonal Antibody 3

Name: Anti-IL-1 beta Polyclonal Antibody 3
Brand: TargetMol
SKU: TMAB-00934
Rating: 4.5 (1 reviews)

Copy Product Info

🥰Excellent

Synonyms:

Catalog No. TMAB-00934 Copy Product Info

🥰Excellent

Anti-IL-1 beta Polyclonal Antibody 3 is a Rabbit antibody targeting IL-1 beta. Anti-IL-1 beta Polyclonal Antibody 3 can be used in WB.

Anti-IL-1 beta Polyclonal Antibody 3

Pack Size	Price	USA Stock	Global Stock
50 μL	$220	7-10 days	7-10 days
100 μL	$373	7-10 days	7-10 days
200 μL	$528	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

Bioactivity

Description	Anti-IL-1 beta Polyclonal Antibody 3 is a Rabbit antibody targeting IL-1 beta. Anti-IL-1 beta Polyclonal Antibody 3 can be used in WB.
Ig Type	IgG
Reactivity	Mouse (predicted:Human,Bee)

Application	WB
Recommended Dose	WB=1:500-2000
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human IL-1 Beta
Antigen Species	Human
Gene Name	IL1B
Gene ID	3553
Protein Name	Interleukin-1 beta
Uniprot ID	P01584
Biology Area	Inflammatory mediators,Interleukins,Obesity,SARS Coronavirus
Function	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.