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Anti-ABP1/AOC1 Antibody (4P152)
😃Good
Catalog No. TMAY-02609
Alias KAO, DAO1, DAO, amine oxidase, copper containing 1, ABP1, ABP
Anti-ABP1/AOC1 Antibody (4P152) is a Mouse antibody targeting ABP1/AOC1. Anti-ABP1/AOC1 Antibody (4P152) can be used in ELISA.
Anti-ABP1/AOC1 Antibody (4P152)
Anti-ABP1/AOC1 Antibody (4P152)
😃Good
Catalog No. TMAY-02609Alias KAO, DAO1, DAO, amine oxidase, copper containing 1, ABP1, ABP
Anti-ABP1/AOC1 Antibody (4P152) is a Mouse antibody targeting ABP1/AOC1. Anti-ABP1/AOC1 Antibody (4P152) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | KAO, DAO1, DAO, amine oxidase, copper containing 1, ABP1, ABP |
| Ig Type | Mouse IgG1 |
| Clone | 4P152 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ABP1/AOC1 (rh ABP1/AOC1; TMPY-00140; AAH14093.1; Met1-Val751). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under control of the proximal AOC1 promoter was significantly enhanced by co-transfection of a WT1 expression construct. Binding of WT1 protein to a cis-regulatory element in the AOC1 promoter was confirmed by electrophoretic mobility shift assay and chromatin immunoprecipitation. WT1-dependent control of polyamine breakdown, which is mediated by changes in AOC1 expression, has a role in kidney organogenesis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ABP1/AOC1 Protein (TMPY-00140) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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