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Annexin A

Annexin is a common name for a group of cellular proteins. They are mostly found in eukaryotic organisms. In humans, the annexins are found inside the cell. However some annexins (Annexin A1, Annexin A2, and Annexin A5) have also been found outside the cellular environment, for example, in blood. How the annexins are transported out of the cell into the blood is currently unknown because they lack a signal peptide necessary for proteins to be transported out of the cell.

  • PY-60
    T95662765218-56-0
    PY-60 potently activates YAP transcriptional activities targeting annexin A2 (Kd = 1.4 µM). PY-60 activates a proproliferative, YAP-dependent transcriptional program in the adult animal capable of remodeling the epidermis through proliferation.
    • $116
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    TargetMol | Inhibitor Hot
  • LCKLSL acetate
    TP2482
    LCKLSL acetate is a competitive annexin A2 (AnxA2) inhibitor. LCKLSL acetate potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2 and the generation of plasmin. LCKLSL acetate has anti-angiogenic roles.
    • $112
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  • Amcinonide
    T026151022-69-6
    Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.
    • $35
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    TargetMol | Citations Cited
  • Dexamethasone acetate
    T09471177-87-3
    Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones.
    • $45
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  • Hydrocortisone acetate
    T124350-03-3
    Hydrocortisone acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties.
    • $47
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  • Hydrocortisone 17-butyrate
    T027013609-67-1
    Hydrocortisone 17-butyrate (Cortisol 17-butyrate) is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.
    • $30
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  • Timonacic
    T0221444-27-9
    Timonacic (Thioproline) has been used in trials studying the treatment of HIV Infections.
    • $29
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