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Anti-RAMP1 Polyclonal Antibody is a Rabbit antibody targeting RAMP1. Anti-RAMP1 Polyclonal Antibody can be used in ELISA,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-RAMP1 Polyclonal Antibody is a Rabbit antibody targeting RAMP1. Anti-RAMP1 Polyclonal Antibody can be used in ELISA,WB. |
| Synonyms | Receptor activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1 |
| Ig Type | IgG |
| Reactivity | Human,Rat |
| Verified Activity | Sample: Lane 1: Rat Heart tissue lysates Lane 2: Rat Pancreas tissue lysates Primary: Anti-RAMP1 (TMAB-01607) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 14 kDa Observed band size: 16 kDa ![]() |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a member of the RAMP family of single transmembrane domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin receptor like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin gene related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. |
| Immunogen | KLH conjugated synthetic peptide: human RAMP1 |
| Antigen Species | Human |
| Gene Name | RAMP1 |
| Gene ID | |
| Protein Name | Receptor activity-modifying protein 1 |
| Uniprot ID | |
| Biology Area | More GPCR,More Neuropeptides,GPCR |
| Function | Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL. |
| Molecular Weight | Theoretical: 14 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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