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Anti-POU2F3 Polyclonal Antibody (Synonyms: Transcription factor Skn-1, Transcription factor PLA-1, transcripti...)
Catalog No. TMAB-01561 Copy Product Info
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Anti-POU2F3 Polyclonal Antibody is a Rabbit antibody targeting POU2F3. Anti-POU2F3 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-POU2F3 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-01561
Synonyms Transcription factor Skn-1, Transcription factor PLA-1, transcription factor 3, POU2F3, POU domain, class 2, transcription factor 3, PLA1, OTF11, Octamer-binding transcription factor 11 (OTF-11), Octamer-binding protein 11 (Oct-11), class 2
Anti-POU2F3 Polyclonal Antibody is a Rabbit antibody targeting POU2F3. Anti-POU2F3 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-POU2F3 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-POU2F3 Polyclonal Antibody is a Rabbit antibody targeting POU2F3. Anti-POU2F3 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Transcription factor Skn-1, Transcription factor PLA-1, transcription factor 3, POU2F3, POU domain, class 2, transcription factor 3, PLA1, OTF11, Octamer-binding transcription factor 11 (OTF-11), Octamer-binding protein 11 (Oct-11), class 2 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Dog,Cow,Rabbit,Sheep) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (rat skin); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (POU2F3) Polyclonal Antibody, Unconjugated (TMAB-01561) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. 2. Sample: Liver (Mouse) Lysate at 40 μg Primary: Anti-POU2F3 (TMAB-01561) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kDa Observed band size: 48 kDa 3. Sample: Testis (Mouse) Lysate at 40 μg Primary: Anti-POU2F3 (TMAB-01561) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kDa Observed band size: 48 kDa    |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Specifically expressed in epidermis and cultured keratinocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] |
| Immunogen | KLH conjugated synthetic peptide: human POU2F3 |
| Antigen Species | Human |
| Gene Name | POU2F3 |
| Gene ID | |
| Protein Name | POU domain, class 2, transcription factor 3 |
| Uniprot ID | |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Regulated the expression of a number of genes such as SPRR2A or placental lactogen. |
| Molecular Weight | Theoretical: 47 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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