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Anti-Histone H2A type 1-B/EAntibody (8L132)

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Catalog No. TMAC-01856

Anti-Histone H2A type 1-B/EAntibody (8L132) is a Rabbit antibody targeting Histone H2A type 1-B/EAntibody (8L132). Anti-Histone H2A type 1-B/EAntibody (8L132) can be used in WB,IHC,ICC/IF.

Anti-Histone H2A type 1-B/EAntibody (8L132)

Anti-Histone H2A type 1-B/EAntibody (8L132)

😃Good
Catalog No. TMAC-01856
Anti-Histone H2A type 1-B/EAntibody (8L132) is a Rabbit antibody targeting Histone H2A type 1-B/EAntibody (8L132). Anti-Histone H2A type 1-B/EAntibody (8L132) can be used in WB,IHC,ICC/IF.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-Histone H2A type 1-B/EAntibody (8L132) is a Rabbit antibody targeting Histone H2A type 1-B/EAntibody (8L132). Anti-Histone H2A type 1-B/EAntibody (8L132) can be used in WB,IHC,ICC/IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundHistone H2A.Z/H2A.F/Z (H2A/z) is a 128 amino acid protein encoded by the human gene H2AFZ. Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA sequentially in a left-handed super-helical turn to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3 and H4) form the octamer, which is comprised of two H2A-H2B dimers and two H3-H4 dimers, creating two nearly symmetrical halves by tertiary structure. H2A.Z/H2A.F/Z is a variant Histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in tran-scription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of posttranslational modifications of histones, also called histone code, and nucleosome remodeling. H2A.Z/H2A.F/Z may be involved in the formation of constitutive heterochromatin and may be required for chromosome segregation during cell division.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 13 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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