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Anti-IGFBP-2 Antibody (5V940)

🥰Excellent
Catalog No. TMAY-03554

Anti-IGFBP-2 Antibody (5V940) is a Rabbit antibody targeting IGFBP-2. Anti-IGFBP-2 Antibody (5V940) can be used in ELISA.

Anti-IGFBP-2 Antibody (5V940)

Anti-IGFBP-2 Antibody (5V940)

🥰Excellent
Catalog No. TMAY-03554
Anti-IGFBP-2 Antibody (5V940) is a Rabbit antibody targeting IGFBP-2. Anti-IGFBP-2 Antibody (5V940) can be used in ELISA.
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Product Introduction

Bioactivity
Description
Anti-IGFBP-2 Antibody (5V940) is a Rabbit antibody targeting IGFBP-2. Anti-IGFBP-2 Antibody (5V940) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
Clone
5V940
Reactivity
Mouse
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse IGFBP-2 / IGFBP2 (rM IGFBP-2 / IGFBP2; TMPY-04213; NP_032368.2; Met1-Gln305).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundIGFBP-2, also known as IGFBP2, is an insulin-like growth factor-binding protein (IGFBP). IGFBPs prolong the half-life of the IGFs, control bioavailability, activity, and distribution of insulin-like growth factor (IGF) through high-affinity IGFBP/IGF complexes. Six high-affinity IGF-binding proteins (IGFBP-1 to -6) have been identified. The six IGFBPs are structurally related but encoded by distinct genes. IGFBPs have a high affinity for IGFs. Some members of the IGFBP family have been consistently shown to inhibit IGF actions by preventing them from gaining access to the IGF receptors, while others potentiate IGF actions by facilitating the ligand-receptor interaction. IGFBP-2 is overexpressed in many malignancies and is often correlated with an increasingly malignant status of the tumor, pointing to the potential involvement of IGFBP-2 in tumorigenesis. It contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. It inhibits IGF-mediated growth and developmental rates.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse IGFBP-2 / IGFBP2 Protein (TMPY-04213)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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