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PDD00017238

Catalog No. T39365 CAS 1952247-05-0

PDD00017238 demonstrates a robust inhibitory effect on Poly(ADP-ribose) Glycohydrolase (PARG), displaying EC50 values of 40 nM in biochemical assay and 55 nM in cell POM assessment.

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PDD00017238, CAS 1952247-05-0

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1 mg	5 days	$ 39.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

PDD00017238 demonstrates a robust inhibitory effect on Poly(ADP-ribose) Glycohydrolase (PARG), displaying EC50 values of 40 nM in biochemical assay and 55 nM in cell POM assessment.

Molecular Weight	476.59
Formula	C19H20N6O3S3
CAS No.	1952247-05-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Dominic I James, et al. First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib. ACS Chem Biol. 2016 Nov 18;11(11):3179-3190.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

PDD00017238 1952247-05-0 PDD-00017238 inhibitor inhibit

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