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Anti-P4HB Antibody (9K753) is a Rabbit antibody targeting P4HB. Anti-P4HB Antibody (9K753) can be used in FCM,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
| Description | Anti-P4HB Antibody (9K753) is a Rabbit antibody targeting P4HB. Anti-P4HB Antibody (9K753) can be used in FCM,WB. |
| Synonyms | prolyl 4-hydroxylase, β polypeptide, prolyl 4-hydroxylase, beta polypeptide, PROHB, PO4HB, PO4DB, PHDB, PDIA1, PDI, P4Hβ, P4Hbeta, GIT, ERBA2L, DSI |
| Ig Type | IgG |
| Clone | 9K753 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of PDI on different lysates using anti-PDI antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3, Lane 2: Human liver. 2. Flow cytometric analysis of Hela cells with PDI antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. ![]() ![]() |
| Application | |
| Recommended Dose | WB: 1:1000-2000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Oxidoreductase-protein disulfide isomerase (PDI) is a homodimer consisting of subunits that catalyzes thiol-disulfide exchange, mediates folding of newly synthesized proteins and functions as a molecular chaperone. PDI localizes to the lumen of the endoplasmic reticulum (ER), where in conjunction with folding-helper proteins, such as immunoglobulin heavy chain binding protein (BiP), mediates tertiary and quaternary protein-processing. Cell surface PDI induces sulfhydryl-mediated conformational changes in integrin-mediated adhesion receptor-ligand interactions, thereby regulating integrin responses and cell adhesion. Additionally, PDI functions as a subunit of two more complex enzyme systems: the prolyl-4-hydroxylase and the triacylglycerol transfer proteins. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 58 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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