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4-hydroperoxy 2-Nonenal

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Catalog No. T36001Cas No. 7439-43-2

4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.

4-hydroperoxy 2-Nonenal

4-hydroperoxy 2-Nonenal

😃Good
Catalog No. T36001Cas No. 7439-43-2
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
500 μg$19535 days35 days
1 mg$35535 days35 days
5 mg$1,43035 days35 days
10 mg$2,58035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, such as linoleic acid and arachidonic acid, that is widely used as a marker of oxidative stress. 4-HNE exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. 4-hydroperoxy 2-Nonenal is the immediate precursor of 4-HNE formed from the cleavage of ω-6 hydroperoxides. Analogous reactions are expected to occur with hydroperoxides from other ω-6 fatty acids, particularly arachidonic acid.
Chemical Properties
Molecular Weight172.224
FormulaC9H16O3
Cas No.7439-43-2
Relative Density.0.999 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol:PBS (pH 7.2)(1:6): 0.5 mg/mL (2.9 mM), Sonication is recommended.
DMF: 30 mg/mL (174.19 mM), Sonication is recommended.
Ethanol: 30 mg/mL (174.19 mM), Sonication is recommended.
DMSO: 30 mg/mL (174.19 mM), Sonication is recommended.
Solution Preparation Table
DMF/Ethanol/DMSO
1mg5mg10mg50mg
5 mM1.1613 mL5.8064 mL11.6128 mL58.0639 mL
10 mM0.5806 mL2.9032 mL5.8064 mL29.0320 mL
20 mM0.2903 mL1.4516 mL2.9032 mL14.5160 mL
50 mM0.1161 mL0.5806 mL1.1613 mL5.8064 mL
100 mM0.0581 mL0.2903 mL0.5806 mL2.9032 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

4hydroperoxy 2Nonenal4-hydroperoxy 2-Nonenal4 hydroperoxy 2 Nonenal
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