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BMAP-28

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Catalog No. T80215Cas No. 184870-31-3

BMAP-28, an antibiotic peptide, induces cell death by triggering the mitochondrial permeability transition pore and serves as a research tool in the study of microbial infections and cancer [1].

BMAP-28

BMAP-28

😃Good
Catalog No. T80215Cas No. 184870-31-3
BMAP-28, an antibiotic peptide, induces cell death by triggering the mitochondrial permeability transition pore and serves as a research tool in the study of microbial infections and cancer [1].
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
BMAP-28, an antibiotic peptide, induces cell death by triggering the mitochondrial permeability transition pore and serves as a research tool in the study of microbial infections and cancer [1].
In vitro
BMAP-28 at a concentration of 3 µM and an incubation time of 10 minutes attenuated calcein fluorescence in the mitochondria of U937 cells [1]. Additionally, BMAP-28 induced depolarization of the mitochondrial inner membrane in both single cells and isolated mitochondria [1].
Chemical Properties
Molecular Weight3073.81
FormulaC145H250N44O29
Cas No.184870-31-3
SmilesC([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(NCC(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(N)=O)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCC3)[C@H](C)C)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCC2)=O)=O)CCCCN)=O)CCCCN)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CN)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CO)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)[C@H](CC)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)C)=O)C=4C=5C(NC4)=CC=CC5
SequenceGly-Gly-Leu-Arg-Ser-Leu-Gly-Arg-Lys-Ile-Leu-Arg-Ala-Trp-Lys-Lys-Tyr-Gly-Pro-Ile-Ile-Val-Pro-Ile-Ile-Arg-Ile-NH2
Sequence ShortGGLRSLGRKILRAWKKYGPIIVPIIRI-NH2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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