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Anti-PLBL2/PLBD2 Antibody (9W739) is a Mouse antibody targeting PLBL2/PLBD2. Anti-PLBL2/PLBD2 Antibody (9W739) can be used in ELISA,ELISA(Det).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μg | $186 | 7-10 days | |
100 μg | $469 | 7-10 days |
Description | Anti-PLBL2/PLBD2 Antibody (9W739) is a Mouse antibody targeting PLBL2/PLBD2. Anti-PLBL2/PLBD2 Antibody (9W739) can be used in ELISA,ELISA(Det). |
Alias | phospholipase B domain containing 2 |
Ig Type | Monoclonal Mouse IgG2a |
Clone | 9W739 |
Reactivity | Chinese hamster |
Application | ELISA,ELISA(Det) |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Chinese hamster PLBL2/PLBD2 (TMPY-06116; G3I6T1-1; Leu38-Asp585). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | PLBD2 localizes to the lysosome, as its absence could plausibly lead to a serious yet unrecognized lysosomal storage disease. PLBD1 and PLBD2 are semi-orphans in the sense of being probable phospholipases of B class but with uncertain physiological substrates and thus functionalities. PLBD1 and PLBD2 constitute a small gene family (sequence homology class) within vertebrates though one that occurs expanded in some early diverging eukaryotes. PLBD2 presents a special difficulty in that a sequence of post-translational steps are apparently necessary for its activation. Without these, potential substrates can hardly be assayed. These steps include removal of the signal peptide, mannosylation appropriate to the lysosome targeting receptor, and self-catalytic proteolytic activation to expose the substrate binding site as this becomes appropriate. |
Conjucates | Unconjugated |
Immunogen | Recombinant Chinese hamster PLBL2/PLBD2 Protein (TMPY-06116) |
Antigen Species | Chinese hamster |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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