FGF-7/KGF Protein, Human, Recombinant

Name: FGF-7/KGF Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPJ-00073
Price: 112 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: KGF, Keratinocyte growth factor, Heparin-binding growth factor 7, HBGF-7, Fibroblast growth factor 7, FGF-7, FGF7) Copy Product Info

Synonyms: KGF, Keratinocyte growth factor, Heparin-binding growth factor 7, HBGF-7, Fibroblast growth factor 7, FGF-7, FGF7

Catalog No. TMPJ-00073 Copy Product Info

Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.

Pack Size	Price	USA Stock	Global Stock
5 µg	$112	-	In Stock
10 µg	$184	-	In Stock
20 µg	$292	-	In Stock
50 µg	$545	-	In Stock
100 µg	$792	7-10 days	7-10 days
200 µg	$1,150	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,970	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Human breast cancer organoids were cultured with Wnt3a, Noggin, R-spondin 3, KGF(Cat#TMPJ-00073), FGF-10, EGF and NRG1-beta 1 (Cat#TMPJ-00448). The organoids showed good morphology.
Description	Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P21781
Amino Acid	Cys32-Thr194
Construction	Cys32-Thr194
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 1 mM EDTA, 5% Trehalose, 0.02% Tween 80, pH 8.0.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	KGF, Keratinocyte growth factor, Heparin-binding growth factor 7, HBGF-7, Fibroblast growth factor 7, FGF-7, FGF7
Research Background	Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.

Chemical Properties

Molecular Weight

17 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.