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Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 μg | $112 | In Stock | |
| 10 μg | $184 | In Stock | |
| 20 μg | $292 | In Stock | |
| 50 μg | $545 | In Stock | |
| 100 μg | $792 | In Stock | |
| 200 μg | $1,150 | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | |
| 1 mg | $2,970 | 7-10 days |
| Biological Activity | Human breast cancer organoids were cultured with Wnt3a, Noggin, R-spondin 3, KGF(Cat#TMPJ-00073), FGF-10, EGF and NRG1-beta 1 (Cat#TMPJ-00448). The organoids showed good morphology. |
| Description | Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation. |
| Species | Human |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | P21781 |
| Synonyms | KGF,Keratinocyte growth factor,Heparin-binding growth factor 7,HBGF-7,Fibroblast growth factor 7,FGF-7,FGF7 |
| Amino Acid | Cys32-Thr194 |
| Construction | Cys32-Thr194 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC. |
| Molecular Weight | 17 KDa (reducing condition) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 1 mM EDTA, 5% Trehalose, 0.02% Tween 80, pH 8.0. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation. |

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