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FGF-7/KGF Protein, Human, Recombinant

(Synonyms: KGF, Keratinocyte growth factor, Heparin-binding growth factor 7, HBGF-7, Fibroblast growth factor 7, FGF-7, FGF7) Copy Product Info
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Synonyms: KGF, Keratinocyte growth factor, Heparin-binding growth factor 7, HBGF-7, Fibroblast growth factor 7, FGF-7, FGF7

Catalog No. TMPJ-00073 Copy Product Info
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Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$112-In Stock
10 μg$184-In Stock
20 μg$292-In Stock
50 μg$545-In Stock
100 μg$7927-10 days7-10 days
200 μg$1,1507-10 days7-10 days
500 μg$1,9007-10 days7-10 days
1 mg$2,9707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Human breast cancer organoids were cultured with Wnt3a, Noggin, R-spondin 3, KGF(Cat#TMPJ-00073), FGF-10, EGF and NRG1-beta 1 (Cat#TMPJ-00448). The organoids showed good morphology.
Description
Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberP21781
Amino AcidCys32-Thr194
ConstructionCys32-Thr194
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. Greater than 95% as determined by SEC-HPLC.
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 1 mM EDTA, 5% Trehalose, 0.02% Tween 80, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsKGF, Keratinocyte growth factor, Heparin-binding growth factor 7, HBGF-7, Fibroblast growth factor 7, FGF-7, FGF7
Research Background
Chemical Properties
Molecular Weight17 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: FGF-7/KGF Protein, Human, Recombinant chemical structure | FGF-7/KGF Protein, Human, Recombinant molecular weight