TGF beta 1 Protein, Mouse/Rat, Recombinant

Name: TGF beta 1 Protein, Mouse/Rat, Recombinant
Brand: TargetMol
SKU: TMPJ-00771
Rating: 4.5 (1 reviews)

(Synonyms: transforming growth factor β-1, transforming growth factor beta-1, TGF-β-1, TGF-β1, TGFβ, TGF-beta-1, TGF-beta 1 protein, TGFbeta, TGF-b1, TGFB1, TGFB, latency-associated peptide, CEDLAP) Copy Product Info

Synonyms: transforming growth factor β-1, transforming growth factor beta-1, TGF-β-1, TGF-β1, TGFβ, TGF-beta-1, TGF-beta 1 protein, TGFbeta, TGF-b1, TGFB1, TGFB, latency-associated peptide, CEDLAP

Catalog No. TMPJ-00771 Copy Product Info

Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

TGF beta 1 Protein, Mouse/Rat, Recombinant

Pack Size	Price	USA Stock	Global Stock
5 µg	$112	7-10 days	7-10 days
10 µg	$183	-	In Stock
20 µg	$292	-	In Stock
50 µg	$545	-	In Stock
100 µg	$845	-	In Stock
200 µg	$1,290	7-10 days	7-10 days
500 µg	$2,360	7-10 days	7-10 days
1 mg	$3,790	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Lyophilized powder

Color:White

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its ability to inhibit IL-4-dependent proliferation of TF‑1 human erythroleukemic cells. The ED50 for this effect is 5-25 pg/ml. (QC verified)
Description	Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
Species	Mouse,Rat
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	P04202
Amino Acid	Ala279-Ser390
Construction	Ala279-Ser390
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 4 mM HCl.
Reconstitution	Reconstitute the lyophilized protein in 4mM HCl. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	transforming growth factor β-1, transforming growth factor beta-1, TGF-β-1, TGF-β1, TGFβ, TGF-beta-1, TGF-beta 1 protein, TGFbeta, TGF-b1, TGFB1, TGFB, latency-associated peptide, CEDLAP
Research Background	Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

Chemical Properties

Molecular Weight

13 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.