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TGF beta 1 Protein, Mouse/Rat, Recombinant

(Synonyms: transforming growth factor β-1, transforming growth factor beta-1, TGF-β-1, TGF-β1, TGFβ, TGF-beta-1, TGF-beta 1 protein, TGFbeta, TGF-b1, TGFB1, TGFB, latency-associated peptide, CEDLAP) Copy Product Info

Synonyms: transforming growth factor β-1, transforming growth factor beta-1, TGF-β-1, TGF-β1, TGFβ, TGF-beta-1, TGF-beta 1 protein, TGFbeta, TGF-b1, TGFB1, TGFB, latency-associated peptide, CEDLAP

Catalog No. TMPJ-00771 Copy Product Info
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
Species
Mouse,Rat
Expression System
HEK293 Cells
TagTag Free
Accession NumberP04202
Amino AcidAla279-Ser390
ConstructionAla279-Ser390
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
https://cdn.targetmol.com/group3/M00/3E/DF/CgoaEWbGogmEag9aAAAAAA_liYM279.png
Endotoxin< 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 4 mM HCl.
ReconstitutionReconstitute the lyophilized protein in 4mM HCl. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonymstransforming growth factor β-1, transforming growth factor beta-1, TGF-β-1, TGF-β1, TGFβ, TGF-beta-1, TGF-beta 1 protein, TGFbeta, TGF-b1, TGFB1, TGFB, latency-associated peptide, CEDLAP
Research Background
Chemical Properties
Molecular Weight13 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: TGF beta 1 Protein, Mouse/Rat, Recombinant chemical structure | TGF beta 1 Protein, Mouse/Rat, Recombinant molecular weight