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TGF beta 1 Protein, Mouse/Rat, Recombinant

Catalog No. TMPJ-00771
Synonyms: TGFB, TGFbeta, CEDLAP, TGF-beta-1, TGF-beta 1 protein, latency-associated peptide, TGF-b1, TGF-β1, transforming growth factor β-1, transforming growth factor beta-1, TGFβ, TGF-β-1, TGFB1

Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
TGF beta 1 Protein, Mouse/Rat, Recombinant
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 2,360.00
1 mg 5 days $ 3,790.00
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Biological Description
Technical Params
Product Properties
Biological Information Measured by its ability to inhibit IL-4-dependent proliferation of TF‑1 human erythroleukemic cells. The ED50 for this effect is 5-25 pg/ml. (QC verified)
Description Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
Species Mouse,Rat
Expression System Human Cells
Tag None
Accession Number P04202
Synonyms TGFB, TGFbeta, CEDLAP, TGF-beta-1, TGF-beta 1 protein, latency-associated peptide, TGF-b1, TGF-β1, transforming growth factor β-1, transforming growth factor beta-1, TGFβ, TGF-β-1, TGFB1
Amino Acid Ala279-Ser390
Construction Recombinant Mouse/Rat Transforming Growth Factor Beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 13 KDa, reducing conditions
Endotoxin Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in 4mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

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Keywords

TGF beta 1 Protein, Mouse/Rat, Recombinant TGFB TGFbeta TGF-β 1 protein CEDLAP TGF-beta-1 TGF-beta 1 protein transforming growth factor b-1 latency-associated peptide TGF-b1 TGFB-1 TGF-β1 transforming growth factor β-1 TGF-b 1 protein transforming growth factor beta-1 TGFB 1 TGF-b-1 TGFβ TGF-β-1 TGFB1 recombinant recombinant-proteins proteins protein

 

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