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Anti-IL-2 R gamma/CD132 Antibody-PE (3J53)
🥰Excellent
Catalog No. TMAY-03091P
Anti-IL-2 R gamma/CD132 Antibody-PE (3J53) is a PE-conjugated Rabbit antibody targeting IL-2 R gamma/CD132. Anti-IL-2 R gamma/CD132 Antibody-PE (3J53) can be used in FCM.
Anti-IL-2 R gamma/CD132 Antibody-PE (3J53)
Anti-IL-2 R gamma/CD132 Antibody-PE (3J53)
🥰Excellent
Catalog No. TMAY-03091P
Anti-IL-2 R gamma/CD132 Antibody-PE (3J53) is a PE-conjugated Rabbit antibody targeting IL-2 R gamma/CD132. Anti-IL-2 R gamma/CD132 Antibody-PE (3J53) can be used in FCM.
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Product Introduction
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Chemical Properties
| Description | Anti-IL-2 R gamma/CD132 Antibody-PE (3J53) is a PE-conjugated Rabbit antibody targeting IL-2 R gamma/CD132. Anti-IL-2 R gamma/CD132 Antibody-PE (3J53) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3J53 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of mouse IL2RG(CD132) expression on mouse splenocytes. BABL/c splenocytes were stained with PE-conjugated anti-Mouse IL2RG(CD132). The histogram were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD132 / IL2RG (rM CD132 / IL2RG; TMPY-01837; NP_038591.1; Met1-Ala263) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL2RG, is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. The common gamma chain (γc) (or IL2RG), is a cytokine receptor subunit that is common to the receptor complexes for at least six different interleukin receptors: IL-2, IL-4, IL-7, IL-9, IL-15, and the interleukin-21 receptor. It is a component of multiple cytokine receptors that are essential for lymphocyte development and function. X-linked severe combined immunodeficiency (X-SCID) is a rare and potentially fatal disease caused by mutations of IL2RG, the gene encoding IL2RG. IL2RG was demonstrated to be a component of the IL-4 receptor based on chemical cross-linking data, the ability of IL2RG to augment IL-4 binding affinity. The observation that IL-2R gamma is a functional component of the IL-4 receptor, together with the finding that IL-2R gamma associates with the IL-7 receptor, begins to elucidate why a deficiency of this common gamma chain (gamma c) has a profound effect on lymphoid function and development, as seen in X-linked severe combined immunodeficiency. |
| Conjucates | PE |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Mouse CD132 / IL2RG protein (TMPY-01837) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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