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PXS-4728A

Name: PXS-4728A
Brand: TargetMol
SKU: T26795
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T26795Cas No. 1478364-68-9

Alias BI-1467335 HCl, BI1467335 HCl, BI 1467335 HCl

BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive pulmonary disease in mice[2].

PXS-4728A

🥰Excellent

Purity: 98.61%

Catalog No. T26795Alias BI-1467335 HCl, BI1467335 HCl, BI 1467335 HClCas No. 1478364-68-9

BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive pulmonary disease in mice[2].

Pack Size	Price	Availability
1 mg	$44	In Stock
2 mg	$62	In Stock
5 mg	$97	In Stock
10 mg	$163	In Stock
25 mg	$347	In Stock
50 mg	$555	In Stock
1 mL x 10 mM (in DMSO)	$97	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.61%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive pulmonary disease in mice[2].
Synonyms	BI-1467335 HCl, BI1467335 HCl, BI 1467335 HCl

Chemical Properties

Molecular Weight	316.8
Formula	C₁₅H₂₂ClFN₂O₂
Cas No.	1478364-68-9
Smiles	Cl.CC(C)(C)NC(=O)c1ccc(OC\C(CN)=C\F)cc1
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 100 mg/mL (315.66 mM), Sonication is recommended.

DMSO: 220 mg/mL (694.44 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (15.78 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1566 mL	15.7828 mL	31.5657 mL	157.8283 mL
5 mM	0.6313 mL	3.1566 mL	6.3131 mL	31.5657 mL
10 mM	0.3157 mL	1.5783 mL	3.1566 mL	15.7828 mL
20 mM	0.1578 mL	0.7891 mL	1.5783 mL	7.8914 mL
50 mM	0.0631 mL	0.3157 mL	0.6313 mL	3.1566 mL
100 mM	0.0316 mL	0.1578 mL	0.3157 mL	1.5783 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc