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Norverapamil-d7 HCl

Name: Norverapamil-d7 HCl
Brand: TargetMol
SKU: TMIH-0399
Rating: 4.5 (1 reviews)

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Catalog No. TMIH-0399Cas No. 1216413-74-9

Alias D591-d7 HCl, D 591-d7 HCl

Norverapamil-d7 HCl (D591-d7 HCl) is a 2H-labeled Norverapamil HCl, a calcium channel blocker and P-glycoprotein (P-gp) inhibitor, used in cardiovascular and neurodegenerative disease research.

Norverapamil-d7 HCl

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Catalog No. TMIH-0399Alias D591-d7 HCl, D 591-d7 HClCas No. 1216413-74-9

Norverapamil-d7 HCl (D591-d7 HCl) is a 2H-labeled Norverapamil HCl, a calcium channel blocker and P-glycoprotein (P-gp) inhibitor, used in cardiovascular and neurodegenerative disease research.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$378	7-10 days	7-10 days
5 mg	$940	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	Norverapamil-d7 HCl (D591-d7 HCl) is a 2H-labeled Norverapamil HCl, a calcium channel blocker and P-glycoprotein (P-gp) inhibitor, used in cardiovascular and neurodegenerative disease research.
Synonyms	D591-d7 HCl, D 591-d7 HCl

Chemical Properties

Molecular Weight	484.08
Formula	C₂₆H₃₇ClN₂O₄
Cas No.	1216413-74-9
Smiles	C(CCCNCCC1=CC(OC)=C(OC)C=C1)(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])(C#N)C2=CC(OC)=C(OC)C=C2.Cl

Storage & Solubility Information

Storage

keep away from moisture | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 10 mg/mL (20.66 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.0658 mL	10.3289 mL	20.6577 mL	103.2887 mL
5 mM	0.4132 mL	2.0658 mL	4.1315 mL	20.6577 mL
10 mM	0.2066 mL	1.0329 mL	2.0658 mL	10.3289 mL
20 mM	0.1033 mL	0.5164 mL	1.0329 mL	5.1644 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc