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Anti-4-1BB Ligand/TNFSF9 Antibody-APC (8F465)
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Catalog No. TMAY-03070A
Anti-4-1BB Ligand/TNFSF9 Antibody-APC (8F465) is a APC-conjugated Rabbit antibody targeting 4-1BB Ligand/TNFSF9. Anti-4-1BB Ligand/TNFSF9 Antibody-APC (8F465) can be used in FCM.
Anti-4-1BB Ligand/TNFSF9 Antibody-APC (8F465)
Anti-4-1BB Ligand/TNFSF9 Antibody-APC (8F465)
🥰Excellent
Catalog No. TMAY-03070A
Anti-4-1BB Ligand/TNFSF9 Antibody-APC (8F465) is a APC-conjugated Rabbit antibody targeting 4-1BB Ligand/TNFSF9. Anti-4-1BB Ligand/TNFSF9 Antibody-APC (8F465) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-4-1BB Ligand/TNFSF9 Antibody-APC (8F465) is a APC-conjugated Rabbit antibody targeting 4-1BB Ligand/TNFSF9. Anti-4-1BB Ligand/TNFSF9 Antibody-APC (8F465) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 8F465 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse 4-1BBL(TNFSF9) expression on RAW264.7 cells. Cells were stained with APC-conjugated anti-Mouse 4-1BBL(TNFSF9). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse 4-1BBL / CD137L / TNFSF9 (rM 4-1BBL / CD137L / TNFSF9; TMPY-00959; NP_033430.1; Arg 104-Glu 309) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | 4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | APC |
| Others Formats | Unconjugated/PerCP/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Mouse 4-1BBL / CD137L / TNFSF9 protein (TMPY-00959) |
| Antigen Species | Mouse |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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