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Sporogen-AO 1
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Catalog No. T36438Cas No. 88418-12-6
Alias Sporogen AO-1
Sporogen-AO 1, a compound from the commensal fungus Penicillium sp. G1-a14, is an inhibitor of human inducible nitric oxide synthase expression with antimalarial activity and strong cytotoxicity.
Sporogen-AO 1
😃Good
Catalog No. T36438Alias Sporogen AO-1Cas No. 88418-12-6
Sporogen-AO 1, a compound from the commensal fungus Penicillium sp. G1-a14, is an inhibitor of human inducible nitric oxide synthase expression with antimalarial activity and strong cytotoxicity.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $548 | 4-6 weeks | 4-6 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Sporogen-AO 1, a compound from the commensal fungus Penicillium sp. G1-a14, is an inhibitor of human inducible nitric oxide synthase expression with antimalarial activity and strong cytotoxicity. |
| Targets&IC50 | Plasmodium falciparum:1.53 μM |
| In vitro | Sporogen-AO 1 showed significant antimalarial effects against Plasmodium falciparum with an IC50=1.53 μM and some cytotoxicity. [1] |
| Synonyms | Sporogen AO-1 |
| Molecular Weight | 248.32 |
| Formula | C15H20O3 |
| Cas No. | 88418-12-6 |
| Smiles | C(C)(=C)[C@]12[C@](O1)([C@@]3(C)C(=CC2=O)CC[C@@H](O)[C@@H]3C)[H] |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Dichloromethane: 1 mg/mL (4.03 mM), Sonication is recommended. DMSO: 1 mg/mL (4.03 mM), Sonication is recommended. Methanol: 1 mg/mL (4.03 mM), Sonication is recommended. Ethanol: 1 mg/mL (4.03 mM), Sonication is recommended. |
Solution Preparation Table | |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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