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GAS6 Protein, Human, Recombinant (His)
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Catalog No. TMPY-04999 Copy Product Info
GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. GAS6 Protein, Human, Recombinant (His) is expressed in HEK293 cells.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $95 | - | In Stock | |
| 10 µg | $156 | 7-10 days | 7-10 days | |
| 20 µg | $258 | 7-10 days | 7-10 days | |
| 50 µg | $588 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 95% as determined by reducing SDS-PAGE
Color:Transparent
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Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | 1. Loaded Anti-Human Gas6 mAb-Fc on Protein A Biosensor, can bind Human GAS6-His with an affinity constant of 5.45 nM as determined in BLI assay. 2. Immobilized Human AXL-His at 10μg/ml (100 μl/well) can bind Human GAS6-His*: Biotinylated by NHS-biotin prior to testing. The ED50 of Recombinant Human GAS6-His* is 0.04466 ug/ml. |
| Description | GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. GAS6 Protein, Human, Recombinant (His) is expressed in HEK293 cells. |
| Expression System | HEK293 cells |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE.  |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Molecular Weight | 72.7 KDa (Predicted), 80-90 KDa (Reducing conditions) |
| Relative Density. | no data available |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: GAS6 Protein, Human, Recombinant (His) chemical structure | GAS6 Protein, Human, Recombinant (His) molecular weight
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