Siglec-6 Protein, Human, Recombinant (hFc)

Name: Siglec-6 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-03961
Rating: 4.5 (1 reviews)

(Synonyms: SIGLEC6, sialic acid binding Ig like lectin 6, OBBP1, CDW327, CD33L2, CD33L1, CD33L, CD327) Copy Product Info

Synonyms: SIGLEC6, sialic acid binding Ig like lectin 6, OBBP1, CDW327, CD33L2, CD33L1, CD33L, CD327

Catalog No. TMPY-03961 Copy Product Info

Siglec-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.5 kDa and the accession number is O43699-3.

Pack Size	Price	USA Stock	Global Stock
5 µg	$68	7-10 days	7-10 days
10 µg	$108	7-10 days	7-10 days
20 µg	$178	7-10 days	7-10 days
50 µg	$359	7-10 days	7-10 days
100 µg	$696	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human Siglec-6, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-Siglec-6 Antibody, hFc Tag with the EC50 of 12.9 ng/ml determined by ELISA (QC Test).
Description	Siglec-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.5 kDa and the accession number is O43699-3.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc (IgG1)
Accession Number	O43699-3
Construction	Gln27-Val331
Protein Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SIGLEC6, sialic acid binding Ig like lectin 6, OBBP1, CDW327, CD33L2, CD33L1, CD33L, CD327
Research Background	SIGLEC6, also known as CD327, belongs to the immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC6 is a sialic acid recognizing protein expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. SIGLEC6 localizes in various compartments such as membrane fraction, extracellular region and so on. SIGLEC6 may show increasing expression human labor and following childbirth, it has been speculated that this expression helps to slow the tempo of human labor. Interestingly, expression of SIGLEC6 is further upregulated in pre-eclampsia, which appears to be a uniquely human disease.

Chemical Properties

Molecular Weight

60.5 kDa (predicted); 75-105 kDa (reducing conditions, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.