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Apronal

Name: Apronal
Brand: TargetMol
SKU: T14314
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14314Cas No. 528-92-7

Alias Apronalide, Allylisopropylacetylurea

Apronal (Apronalide) has the hypnotic and sedative capacity and can be used for studies about neuropsychiatry disorders.

Apronal

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Purity: 99.84%

Catalog No. T14314Alias Apronalide, AllylisopropylacetylureaCas No. 528-92-7

Apronal (Apronalide) has the hypnotic and sedative capacity and can be used for studies about neuropsychiatry disorders.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$34	-	In Stock
1 mL x 10 mM (in DMSO)	$50	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.84%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Apronal (Apronalide) has the hypnotic and sedative capacity and can be used for studies about neuropsychiatry disorders.
In vivo	Fixed drug eruption and mucocutaneous ocular syndrome are reported due to Apronal[1]. Apronal not only increases the amount of porphyrins in the liver and urine of animals but also brings about a marked green pigmentation of the liver. Rats recover well from long-term treatment with high doses of Apronal and revert to normal values for parameters measured. Lesions originated by long-term administration with Apronal can be tolerated by rats and are reversible[2].
Synonyms	Apronalide, Allylisopropylacetylurea

Chemical Properties

Molecular Weight	184.24
Formula	C₉H₁₆N₂O₂
Cas No.	528-92-7
Smiles	CC(C)C(CC=C)C(=O)NC(N)=O
Relative Density.	1.1111 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 145 mg/mL (787.02 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 4 mg/mL (21.71 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.4277 mL	27.1385 mL	54.2770 mL	271.3851 mL
5 mM	1.0855 mL	5.4277 mL	10.8554 mL	54.2770 mL
10 mM	0.5428 mL	2.7139 mL	5.4277 mL	27.1385 mL
20 mM	0.2714 mL	1.3569 mL	2.7139 mL	13.5693 mL
50 mM	0.1086 mL	0.5428 mL	1.0855 mL	5.4277 mL
100 mM	0.0543 mL	0.2714 mL	0.5428 mL	2.7139 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc