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Apronal

Name: Apronal
Brand: TargetMol
SKU: T14314
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14314Cas No. 528-92-7

Alias Apronalide, Allylisopropylacetylurea

Apronal (Apronalide) has the hypnotic and sedative capacity and can be used for studies about neuropsychiatry disorders.

Apronal

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Purity: 99.84%

Catalog No. T14314Alias Apronalide, AllylisopropylacetylureaCas No. 528-92-7

Apronal (Apronalide) has the hypnotic and sedative capacity and can be used for studies about neuropsychiatry disorders.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$34	-	In Stock
1 mL x 10 mM (in DMSO)	$50	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.84%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Apronal (Apronalide) has the hypnotic and sedative capacity and can be used for studies about neuropsychiatry disorders.
In vivo	Fixed drug eruption and mucocutaneous ocular syndrome are reported due to Apronal[1]. Apronal not only increases the amount of porphyrins in the liver and urine of animals but also brings about a marked green pigmentation of the liver. Rats recover well from long-term treatment with high doses of Apronal and revert to normal values for parameters measured. Lesions originated by long-term administration with Apronal can be tolerated by rats and are reversible[2].
Synonyms	Apronalide, Allylisopropylacetylurea

Chemical Properties

Molecular Weight	184.24
Formula	C₉H₁₆N₂O₂
Cas No.	528-92-7
Smiles	CC(C)C(CC=C)C(=O)NC(N)=O
Relative Density.	1.1111 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 145 mg/mL (787.02 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 4 mg/mL (21.71 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.4277 mL	27.1385 mL	54.2770 mL	271.3851 mL
5 mM	1.0855 mL	5.4277 mL	10.8554 mL	54.2770 mL
10 mM	0.5428 mL	2.7139 mL	5.4277 mL	27.1385 mL
20 mM	0.2714 mL	1.3569 mL	2.7139 mL	13.5693 mL
50 mM	0.1086 mL	0.5428 mL	1.0855 mL	5.4277 mL
100 mM	0.0543 mL	0.2714 mL	0.5428 mL	2.7139 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc