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Anti-Caspase-14 Antibody (5W237)
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Catalog No. TMAY-02109
Alias caspase 14, apoptosis-related cysteine peptidase, ARCI12
Anti-Caspase-14 Antibody (5W237) is a Mouse antibody targeting Caspase-14. Anti-Caspase-14 Antibody (5W237) can be used in ELISA,FCM.
Anti-Caspase-14 Antibody (5W237)
Anti-Caspase-14 Antibody (5W237)
😃Good
Catalog No. TMAY-02109Alias caspase 14, apoptosis-related cysteine peptidase, ARCI12
Anti-Caspase-14 Antibody (5W237) is a Mouse antibody targeting Caspase-14. Anti-Caspase-14 Antibody (5W237) can be used in ELISA,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Mouse Monoclonal Application: ELISA, FCM Reactivity: Human |
| Alias | caspase 14, apoptosis-related cysteine peptidase, ARCI12 |
| Ig Type | Mouse IgG2b |
| Clone | 5W237 |
| Reactivity | Human |
| Verified Activity | Human CASP14 expression in HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and stained with Purified Mouse anti-CASP14, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | ELISA,FCM |
| Recommended Dose | ELISA: 1:1000-1:2000; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Caspase 14 was not processed by multiple death stimuli including activation of members of the tumor necrosis factor receptor family and expression of proapaptotic members of the bcl-2 family. Caspase 14 has been described to be processed and activated by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may take part in keratinocyte terminal differentiation, which is essential for the skin barrier. |
| Conjucates | Unconjugated |
| Others Formats | FITC |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Human Caspase-14 Protein (TMPY-01824) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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