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Fenoldopam mesylate

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Catalog No. T6835Cas No. 67227-57-0
Alias SKF-82526 mesylate, Fenoldopam methanesulfonate, Corlopam mesylate

Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.

Fenoldopam mesylate

Fenoldopam mesylate

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Purity: 99.94%
Catalog No. T6835Alias SKF-82526 mesylate, Fenoldopam methanesulfonate, Corlopam mesylateCas No. 67227-57-0
Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$43In StockIn Stock
25 mg$82In StockIn Stock
50 mg$153In StockIn Stock
100 mg$221In StockIn Stock
200 mg$339In Stock-
1 mL x 10 mM (in DMSO)$48In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.94%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
In vivo
Fenoldopam (20 μg/kg) induced a marked decrease in systolic blood pressure, diastolic blood pressure and heart rate[1].
SynonymsSKF-82526 mesylate, Fenoldopam methanesulfonate, Corlopam mesylate
Chemical Properties
Molecular Weight401.86
FormulaC16H16ClNO3·CH4O3S
Cas No.67227-57-0
SmilesCS(O)(=O)=O.Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12
Relative Density.1.38g/cm3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 74 mg/mL (184.14 mM), Sonication is recommended.
H2O: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4884 mL12.4421 mL24.8843 mL124.4214 mL
5 mM0.4977 mL2.4884 mL4.9769 mL24.8843 mL
10 mM0.2488 mL1.2442 mL2.4884 mL12.4421 mL
20 mM0.1244 mL0.6221 mL1.2442 mL6.2211 mL
50 mM0.0498 mL0.2488 mL0.4977 mL2.4884 mL
100 mM0.0249 mL0.1244 mL0.2488 mL1.2442 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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