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Anti-OST beta Polyclonal Antibody

😃Good
Catalog No. TMAB-01292
Alias Ostbeta, OSTB, Ost beta, Organic solute transporter subunit beta, organic solute transporter beta(Ostbeta)

Anti-OST beta Polyclonal Antibody is a Rabbit antibody targeting OST beta. Anti-OST beta Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,ELISA.

Anti-OST beta Polyclonal Antibody

Anti-OST beta Polyclonal Antibody

😃Good
Catalog No. TMAB-01292Alias Ostbeta, OSTB, Ost beta, Organic solute transporter subunit beta, organic solute transporter beta(Ostbeta)
Anti-OST beta Polyclonal Antibody is a Rabbit antibody targeting OST beta. Anti-OST beta Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2207-10 days
100 μL$3747-10 days
200 μL$5277-10 days
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Product Introduction

Bioactivity
Description
Anti-OST beta Polyclonal Antibody is a Rabbit antibody targeting OST beta. Anti-OST beta Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,ELISA.
AliasOstbeta, OSTB, Ost beta, Organic solute transporter subunit beta, organic solute transporter beta(Ostbeta)
Ig Type
IgG
Reactivity
(predicted:Human,Mouse,Rat)
Application
IHC-P,IHC-Fr,IF,ELISA
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane. Mainly restricted to the lateral and basal membranes of ileal enterocytes.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThe heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human OST-beta
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Channels
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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