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Anti-OST beta Polyclonal Antibody
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Catalog No. TMAB-01292
Alias Ostbeta, OSTB, Ost beta, Organic solute transporter subunit beta, organic solute transporter beta(Ostbeta)
Anti-OST beta Polyclonal Antibody is a Rabbit antibody targeting OST beta. Anti-OST beta Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,ELISA.
Anti-OST beta Polyclonal Antibody
Anti-OST beta Polyclonal Antibody
😃Good
Catalog No. TMAB-01292Alias Ostbeta, OSTB, Ost beta, Organic solute transporter subunit beta, organic solute transporter beta(Ostbeta)
Anti-OST beta Polyclonal Antibody is a Rabbit antibody targeting OST beta. Anti-OST beta Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-OST beta Polyclonal Antibody is a Rabbit antibody targeting OST beta. Anti-OST beta Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,ELISA. |
| Alias | Ostbeta, OSTB, Ost beta, Organic solute transporter subunit beta, organic solute transporter beta(Ostbeta) |
| Ig Type | IgG |
| Reactivity | (predicted:Human,Mouse,Rat) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. Mainly restricted to the lateral and basal membranes of ileal enterocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum. |
| Immunogen | KLH conjugated synthetic peptide: human OST-beta |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Channels |
| Molecular Weight | Theoretical: 14 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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