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Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)

Catalog No. TMPY-00248
Synonyms: Lymphotoxin β, lymphotoxin β (TNF superfamily, member 3), lymphotoxin beta (TNF superfamily, member 3)

LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. Heat-labile enterotoxin B subunit (LTB) of enterotoxigenic Escherichia coli (ETEC) is both a strong mucosal adjuvant and immunogen. It is a subunit vaccine candidate to be used against ETEC-induced diarrhea. It has already been expressed in several bacterial and plant systems.LTB provokes a systemic immune response and exerts adjuvant effects on mucosal immune responses to unrelated antigens. Diseases associated with LTB include Synovitis and Myasthenic Syndrome, Congenital, 2C, Associated With Acetylcholine Receptor Deficiency.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His)
Pack Size Availability Price/USD Quantity
50 μg 5 days $ 462.00
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Biological Description
Technical Params
Product Properties
Description LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. Heat-labile enterotoxin B subunit (LTB) of enterotoxigenic Escherichia coli (ETEC) is both a strong mucosal adjuvant and immunogen. It is a subunit vaccine candidate to be used against ETEC-induced diarrhea. It has already been expressed in several bacterial and plant systems.LTB provokes a systemic immune response and exerts adjuvant effects on mucosal immune responses to unrelated antigens. Diseases associated with LTB include Synovitis and Myasthenic Syndrome, Congenital, 2C, Associated With Acetylcholine Receptor Deficiency.
Species Cynomolgus
Expression System Baculovirus-Insect Cells
Tag His
Accession Number XP_003897389.1
Synonyms Lymphotoxin β, lymphotoxin β (TNF superfamily, member 3), lymphotoxin beta (TNF superfamily, member 3)
Construction A DNA sequence encoding the cynomolgus LTB (XP_003897389.1) (Gln49-Gly244) was expressed with a polyhistidine tag at the N-terminus.
Protein Purity > 90 % as determined by SDS-PAGE.
Molecular Weight Approxiamtely 22.8 kDa
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Formulation Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background LTB (Lymphotoxin Beta) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. Heat-labile enterotoxin B subunit (LTB) of enterotoxigenic Escherichia coli (ETEC) is both a strong mucosal adjuvant and immunogen. It is a subunit vaccine candidate to be used against ETEC-induced diarrhea. It has already been expressed in several bacterial and plant systems.LTB provokes a systemic immune response and exerts adjuvant effects on mucosal immune responses to unrelated antigens. Diseases associated with LTB include Synovitis and Myasthenic Syndrome, Congenital, 2C, Associated With Acetylcholine Receptor Deficiency.

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Keywords

Lymphotoxin Beta Protein, Cynomolgus, Recombinant (His) TNF superfamily, member 3 Lymphotoxin β lymphotoxin beta lymphotoxin β (TNF superfamily, member 3) lymphotoxin beta (TNF superfamily, member 3) recombinant recombinant-proteins proteins protein

 

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