keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
[D-Phe2,6, Pro3]-LH-RH is a potent antagonist of luteinizing hormone-releasing hormone (LHRH).
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Description | [D-Phe2,6, Pro3]-LH-RH is a potent antagonist of luteinizing hormone-releasing hormone (LHRH). |
In vitro | [D-Phe2,6, Pro3]-LH-RH (0.')'>The compound [D-Phe2,6, Pro3]-LH-RH demonstrates agonistic activity, binding to gonadotropin-releasing hormone receptors, thereby stimulating the secretion of luteinizing hormone and follicle-stimulating hormone. This leads to an increase in the synthesis of testosterone and estrogen, respectively. |
In vivo | "[D-Phe2,6, Pro3]-LH-RH (300 mg/monkey, SC, 50 mg/injection; six injections) effectively suppresses spontaneous preovulatory gonadotropin peaks, thereby preventing ovulation in rhesus monkeys [1]. A single dose of [D-Phe2,6, Pro3]-LH-RH (750 μg administered at 12:00 h on proestrus day) achieves 100% inhibition of ovulation in rats [1]." |
Molecular Weight | 1193.35 |
Formula | C59H80N14O13 |
CAS No. | 64789-67-9 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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[D-Phe2,6, Pro3]-LH-RH 64789-67-9 inhibitor inhibit