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Anti-SCNN1A Polyclonal Antibody

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Catalog No. TMAB-01669
Alias sodium channel epithelial 1 subunit alpha, SCNNA, SCNN1, SCNEA, PHA1B1, Nonvoltage-gated sodium channel 1 subunit alpha, LIDLS3, Epithelial Na(+) channel subunit alpha(alpha-ENaC, ENaCalpha, ENaCA), ENaCa, BESC2, Amiloride-sensitive sodium channel subunit alpha, alpha-NaCH

Anti-SCNN1A Polyclonal Antibody is a Rabbit antibody targeting SCNN1A. Anti-SCNN1A Polyclonal Antibody can be used in WB.

Anti-SCNN1A Polyclonal Antibody

Anti-SCNN1A Polyclonal Antibody

😃Good
Catalog No. TMAB-01669Alias sodium channel epithelial 1 subunit alpha, SCNNA, SCNN1, SCNEA, PHA1B1, Nonvoltage-gated sodium channel 1 subunit alpha, LIDLS3, Epithelial Na(+) channel subunit alpha(alpha-ENaC, ENaCalpha, ENaCA), ENaCa, BESC2, Amiloride-sensitive sodium channel subunit alpha, alpha-NaCH
Anti-SCNN1A Polyclonal Antibody is a Rabbit antibody targeting SCNN1A. Anti-SCNN1A Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2217-10 days
100 μL$3747-10 days
200 μL$5297-10 days
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Product Introduction

Bioactivity
Description
Anti-SCNN1A Polyclonal Antibody is a Rabbit antibody targeting SCNN1A. Anti-SCNN1A Polyclonal Antibody can be used in WB.
Synonymssodium channel epithelial 1 subunit alpha, SCNNA, SCNN1, SCNEA, PHA1B1, Nonvoltage-gated sodium channel 1 subunit alpha, LIDLS3, Epithelial Na(+) channel subunit alpha(alpha-ENaC, ENaCalpha, ENaCA), ENaCa, BESC2, Amiloride-sensitive sodium channel subunit alpha, alpha-NaCH
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat)
Verified Activity
25 μg total protein per Lane of various lysates probed with SCNN1A polyclonal antibody, unconjugated (TMAB-01669) at 1:500 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
Application
Recommended Dose
WB: 1:200-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationApical cell membrane; Multi-pass membrane protein.
Tissue SpecificityHighly expressed in kidney and lung. Detected at intermediate levels in pancreas and liver, and at low levels in heart and placenta. Isoform 1 and isoform 2 predominate in all tissues. Expression of isoform 3, isoform 4 and isoform 5 is very low or not de
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundSodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Alpha-ENaC
Antigen Species
Human
Gene Name
SCNN1A
Gene ID
Protein Name
Epithelial sodium channel subunit alpha
Uniprot ID
Biology Area
Sodium Channels,Channels
Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Chemical Properties
Molecular WeightTheoretical: 76 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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