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M-CSF/CSF1 Protein, Cynomolgus, Recombinant (His)

(Synonyms: MGC31930, M-CSF, MCSF, Lanimostim, CSF-1, CSF1) Copy Product Info

Synonyms: MGC31930, M-CSF, MCSF, Lanimostim, CSF-1, CSF1

Catalog No. TMPK-01325 Copy Product Info
M-CSF/CSF1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.26 kDa and the accession number is XP_045221641.1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$487-10 days7-10 days
10 µg$767-10 days7-10 days
20 µg$1227-10 days7-10 days
50 µg$2367-10 days7-10 days
100 µg$3937-10 days7-10 days
200 µg$7127-10 days7-10 days
500 µg$1,5707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Cynomolgus M-CSF R, His Tag immobilized on CM5 Chip can bind Cynomolgus M-CSF, His Tag with an affinity constant of 0.889 μM as determined in SPR assay.
Description
M-CSF/CSF1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.26 kDa and the accession number is XP_045221641.1.
Species
Cynomolgus
Expression System
HEK293 Cells
TagC-His
Accession NumberXP_045221641.1
ConstructionGlu33-Leu255
Protein Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsMGC31930, M-CSF, MCSF, Lanimostim, CSF-1, CSF1
Research Background
CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand.
Chemical Properties
Molecular Weight26.26 kDa (predicted). Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: M-CSF/CSF1 Protein, Cynomolgus, Recombinant (His) chemical structure | M-CSF/CSF1 Protein, Cynomolgus, Recombinant (His) molecular weight