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Dinoprost

🥰Excellent
Catalog No. T15133Cas No. 551-11-1
Alias Prostaglandin F2a, PGF2α

Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.

Dinoprost
Other Forms of Dinoprost:

Dinoprost

🥰Excellent
Purity: 98.04%
Catalog No. T15133Alias Prostaglandin F2a, PGF2αCas No. 551-11-1
Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$47In StockIn Stock
10 mg$72In StockIn Stock
25 mg$147In StockIn Stock
50 mg$228-In Stock
100 mg$363-In Stock
200 mg$538-In Stock
1 mL x 10 mM (in DMSO)$52-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.04%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.
In vitro
Dinoprost (Prostaglandin F2α; 1 μM; 24 hours) induces ER stress, autophagy, and apoptosis in goat luteal cells and significantly increases the expression of GRP78 and UPR sensors[3].
SynonymsProstaglandin F2a, PGF2α
Chemical Properties
Molecular Weight354.48
FormulaC20H34O5
Cas No.551-11-1
SmilesCCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Relative Density.1.153 g/cm3
ColorYellow
AppearanceViscous
Storage & Solubility Information
Storagestore at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 100 mg/mL (282.1 mM), Sonication is recommended.
DMSO: 100 mg/mL (282.1 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (11.28 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.8210 mL14.1052 mL28.2103 mL141.0517 mL
5 mM0.5642 mL2.8210 mL5.6421 mL28.2103 mL
10 mM0.2821 mL1.4105 mL2.8210 mL14.1052 mL
20 mM0.1411 mL0.7053 mL1.4105 mL7.0526 mL
50 mM0.0564 mL0.2821 mL0.5642 mL2.8210 mL
100 mM0.0282 mL0.1411 mL0.2821 mL1.4105 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

stressProstaglandin ReceptorProstaglandin F2αPGF2alphaPGF2aluteumluteolyticluminallabourInhibitorinhibitHuman Endogenous MetabolitehormoneepitheliumEndogenousMetaboliteEndogenous MetaboliteDinoprostcorpusAutophagyApoptosis
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