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Anti-Progranulin Antibody-HRP (2T113) (Synonyms: Pgrn, Granulin Precursor, epithelin)
Catalog No. TMAY-03267H Copy Product Info
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Anti-Progranulin Antibody-HRP (2T113) is a HRP-conjugated Rabbit antibody targeting Progranulin. Anti-Progranulin Antibody-HRP (2T113) can be used in ELISA.
Anti-Progranulin Antibody-HRP (2T113)
Copy Product Info🥰Excellent
Catalog No. TMAY-03267H
Synonyms Pgrn, Granulin Precursor, epithelin
Anti-Progranulin Antibody-HRP (2T113) is a HRP-conjugated Rabbit antibody targeting Progranulin. Anti-Progranulin Antibody-HRP (2T113) can be used in ELISA.
Anti-Progranulin Antibody-HRP
(2T113)
(2T113)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μg | $410 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Progranulin Antibody-HRP (2T113) is a HRP-conjugated Rabbit antibody targeting Progranulin. Anti-Progranulin Antibody-HRP (2T113) can be used in ELISA. |
| Synonyms | Pgrn, Granulin Precursor, epithelin |
| Ig Type | Rabbit IgG |
| Clone | 2T113 |
| Reactivity | Mouse |
| Specificity | Mouse Progranulin |
| Application | |
| Recommended Dose | ELISA: 0.1-1 μg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Progranulin / Granulin (rM Progranulin / Granulin; TMPY-01435; NP_032201.2; Met1-Leu589), and conjugated with horseradish-peroxidase (HRP). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, is also called Proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth. Granulin expression inhibited Tat transactivation, and tethering experiments showed that this effect was due, at least in part, to a direct action on cyclin T1 in the absence of Tat. |
| Conjucates | HRP |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Mouse Progranulin / Granulin Protein (TMPY-01435) |
| Antigen Species | Mouse |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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