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TargetMol | Compound Library

Anti-Gram-Positive Bacterial Library

Catalog No. L4522

Gram-positive bacteria are a group of bacteria that appear purple in the Gram staining test. They have thick cell walls rich in peptidoglycan and lack an outer membrane structure. Common pathogenic Gram-positive bacteria include *Staphylococcus aureus*, methicillin-resistant *Staphylococcus aureus* (MRSA), *Streptococcus pneumoniae*, *Enterococcus* spp., and *Bacillus anthracis*. These pathogens can cause a variety of serious diseases such as skin and soft tissue infections, pneumonia, sepsis, and endocarditis, and hold significant clinical relevance in both hospital-acquired and community-acquired infections.
With the widespread use of antibiotics, the issue of antibiotic resistance in Gram-positive bacteria has become increasingly severe. In particular, the emergence and spread of “superbugs” such as MRSA and vancomycin-resistant enterococci (VRE) have greatly reduced the efficacy of traditional antibiotics, including β-lactams, macrolides, and even glycopeptides, leading to higher treatment failure rates and increased mortality risk. There is an urgent need to develop novel, effective, and safe anti-Gram-positive bacterial agents.
The TargetMol’s anti-gram-positive bacteria compound library contains 275 small-molecule compounds with activity against Gram-positive bacteria. It serves as a powerful tool for antibacterial drug research, aiming to provide high-quality lead compound resources to overcome the challenge of drug resistance.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L4522

Anti-Gram-Positive Bacterial Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unqie collection of 275 anti gram-positive bacteria compounds for high throughput screening (HTS) and high content screening (HCS);
  • Powerful tool for anti-bacteria study;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Antibacterial
Antibiotic
Autophagy
Parasite
Antifungal
Topoisomerase
DNA/RNA Synthesis
ribosome
Apoptosis
Endogenous Metabolite
DNA gyrase
Antifection
COX
Cytochromes P450
DHFR
HIV Protease
HSP
Reactive Oxygen Species
ROS
Anti-infection
Dehydrogenase
Ferroptosis
Influenza Virus
NF-κB
Virus Protease
AMPK
Chloride channel
DNA Methyltransferase
DUB
Estrogen/progestogen Receptor
HSV
IκB/IKK
MicroRNA
MRP
Potassium Channel
Proton pump
SARS-CoV
Thrombin
Wnt/beta-catenin
Acetyl-CoA Carboxylase
Antifolate
Antioxidant
Aromatase
Bcr-Abl
Calcium Channel
cAMP
Carbonic Anhydrase
Caspase
Cell wall
CXCR
Dopamine Receptor
Drug Metabolite
Endothelin Receptor
Estrogen Receptor/ERR
Fatty Acid Synthase
Glucosidase
Glutathione Peroxidase
Glutathione reductase
GlyT
HBV
Histamine Receptor
IGF-1R
iGluR
Immunology/Inflammation related
JNK
MAO
Mitochondrial Metabolism
MMP
NADPH
NOS
Nrf2
Nucleoside Antimetabolite/Analog
P2Y Receptor
PD-1/PD-L1
Phospholipase
PKC
PKM
PPAR
Pyroptosis
Retinoid Receptor
S6 Kinase
Src
STAT
Thrombopoietin Receptor
TNF
TOPK
Xanthine Oxidase

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