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TargetMol | Compound Library

Anti-Gram-Positive Bacterial Library

Catalog No. L4522

Gram-positive bacteria are a group of bacteria that appear purple in the Gram staining test. They have thick cell walls rich in peptidoglycan and lack an outer membrane structure. Common pathogenic Gram-positive bacteria include *Staphylococcus aureus*, methicillin-resistant *Staphylococcus aureus* (MRSA), *Streptococcus pneumoniae*, *Enterococcus* spp., and *Bacillus anthracis*. These pathogens can cause a variety of serious diseases such as skin and soft tissue infections, pneumonia, sepsis, and endocarditis, and hold significant clinical relevance in both hospital-acquired and community-acquired infections.
With the widespread use of antibiotics, the issue of antibiotic resistance in Gram-positive bacteria has become increasingly severe. In particular, the emergence and spread of “superbugs” such as MRSA and vancomycin-resistant enterococci (VRE) have greatly reduced the efficacy of traditional antibiotics, including β-lactams, macrolides, and even glycopeptides, leading to higher treatment failure rates and increased mortality risk. There is an urgent need to develop novel, effective, and safe anti-Gram-positive bacterial agents.
The TargetMol’s anti-gram-positive bacteria compound library contains 275 small-molecule compounds with activity against Gram-positive bacteria. It serves as a powerful tool for antibacterial drug research, aiming to provide high-quality lead compound resources to overcome the challenge of drug resistance.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L4522

Anti-Gram-Positive Bacterial Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unqie collection of 275 anti gram-positive bacteria compounds for high throughput screening (HTS) and high content screening (HCS);
  • Powerful tool for anti-bacteria study;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Antibacterial
Antibiotic
Autophagy
Parasite
Antifungal
Topoisomerase
DNA/RNA Synthesis
ribosome
Apoptosis
Endogenous Metabolite
DNA gyrase
Antifection
COX
HIV Protease
DHFR
ROS
Reactive Oxygen Species
Cytochromes P450
HSP
Dehydrogenase
Ferroptosis
Virus Protease
Influenza Virus
NF-κB
Anti-infection
Chloride channel
Proton pump
MicroRNA
Estrogen/progestogen Receptor
MRP
Wnt/beta-catenin
HSV
DUB
SARS-CoV
IκB/IKK
AMPK
Potassium Channel
DNA Methyltransferase
Thrombin
NOS
Carbonic Anhydrase
Dopamine Receptor
Src
Antioxidant
P2Y Receptor
Cell wall
NADPH
Histamine Receptor
JNK
Glutathione Peroxidase
TOPK
Estrogen Receptor/ERR
HBV
PPAR
Photosensitizer
Antifolate
Nucleoside Antimetabolite/Analog
Caspase
Calcium Channel
PKC
MAO
iGluR
Immunology/Inflammation related
Bcr-Abl
Drug Metabolite
GlyT
Mitochondrial Metabolism
Glucosidase
Fatty Acid Synthase
CXCR
Endothelin Receptor
MMP
Xanthine Oxidase
cAMP
Thrombopoietin Receptor
IGF-1R
Glutathione reductase
Nrf2
Pyroptosis
Acetyl-CoA Carboxylase
Retinoid Receptor
STAT
Aromatase
Phospholipase
TNF
S6 Kinase
PD-1/PD-L1
PKM

Keywords