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Kaempferol 3-O-β-D-glucuronide

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Catalog No. TN1818Cas No. 22688-78-4
Alias Kaempferol-3-O-glucuronide, Kaempferol-3-glucuronide, Kaempferol-3-beta-O-glucuronide

Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-beta-O-glucuronide) exhibits antioxidant activity. Flavonoid glucuronides can be deconjugated by microsomal α²-glucuronidase from various human cells.

Kaempferol 3-O-β-D-glucuronide

Kaempferol 3-O-β-D-glucuronide

😃Good
Purity: 99.8%
Catalog No. TN1818Alias Kaempferol-3-O-glucuronide, Kaempferol-3-glucuronide, Kaempferol-3-beta-O-glucuronideCas No. 22688-78-4
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-beta-O-glucuronide) exhibits antioxidant activity. Flavonoid glucuronides can be deconjugated by microsomal α²-glucuronidase from various human cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$93In StockIn Stock
5 mg$278In StockIn Stock
10 mg$412-In Stock
25 mg$686-In Stock
50 mg$977-In Stock
100 mg$1,320-In Stock
1 mL x 10 mM (in DMSO)$285-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.8%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-beta-O-glucuronide) exhibits antioxidant activity. Flavonoid glucuronides can be deconjugated by microsomal α²-glucuronidase from various human cells.
In vitro
Kaempferol-3-o-β-d-glucuronate exhibit potential anti-inflammatory effect in LPS stimulated RAW 264.7 cells[2].
In vivo
Kaempferol-3-o-β-d-glucuronate exhibit potential anti-inflammatory effect in mice model[2].
SynonymsKaempferol-3-O-glucuronide, Kaempferol-3-glucuronide, Kaempferol-3-beta-O-glucuronide
Chemical Properties
Molecular Weight462.36
FormulaC21H18O12
Cas No.22688-78-4
SmilesO[C@H]1[C@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2ccc(O)cc2)O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O
Relative Density.1.87
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 1 mg/mL (2.16 mM), Sonication and heating to 37℃ are recommended.
DMSO: 95 mg/mL (205.47 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (7.14 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.1628 mL10.8141 mL21.6282 mL108.1408 mL
DMSO
1mg5mg10mg50mg
5 mM0.4326 mL2.1628 mL4.3256 mL21.6282 mL
10 mM0.2163 mL1.0814 mL2.1628 mL10.8141 mL
20 mM0.1081 mL0.5407 mL1.0814 mL5.4070 mL
50 mM0.0433 mL0.2163 mL0.4326 mL2.1628 mL
100 mM0.0216 mL0.1081 mL0.2163 mL1.0814 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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