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Anti-LC3B Polyclonal Antibody 2 (Synonyms: microtubule-associated protein 1 light chain 3 β, microtubule-associ...)
Catalog No. TMAB-01053 Copy Product Info
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Anti-LC3B Polyclonal Antibody 2 is a Rabbit antibody targeting LC3B. Anti-LC3B Polyclonal Antibody 2 can be used in WB.
Anti-LC3B Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-01053
Synonyms microtubule-associated protein 1 light chain 3 β, microtubule-associated protein 1 light chain 3 beta, MAP1LC3B-a, MAP1A/1BLC3, LC3B, ATG8F
Anti-LC3B Polyclonal Antibody 2 is a Rabbit antibody targeting LC3B. Anti-LC3B Polyclonal Antibody 2 can be used in WB.
Anti-LC3B Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Antigen Details
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| Description | Anti-LC3B Polyclonal Antibody 2 is a Rabbit antibody targeting LC3B. Anti-LC3B Polyclonal Antibody 2 can be used in WB. |
| Synonyms | microtubule-associated protein 1 light chain 3 β, microtubule-associated protein 1 light chain 3 beta, MAP1LC3B-a, MAP1A/1BLC3, LC3B, ATG8F |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Cerebellum tissue lysates Lane 3: Mouse Testis tissue lysates Lane 4: Rat Cerebrum tissue lysates Lane 5: Rat Cerebellum tissue lysates Lane 6: Rat Testis tissue lysates Primary: Anti-LC3B (TMAB-01053) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 14 kDa Observed band size: 15,17 kDa  |
| Application | |
| Recommended Dose | WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasmic. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note: LC3B binds to the autophagic membranes. |
| Tissue Specificity | Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy. |
| Immunogen | KLH conjugated synthetic peptide: mouse LC3B |
| Antigen Species | Mouse |
| Gene Name | MAP1LC3B |
| Gene ID | |
| Protein Name | Microtubule-associated proteins 1A/1B light chain 3B |
| Uniprot ID | |
| Biology Area | APG gene products,Signal Transduction,Autophagy,APG gene products,Autophagy and mitophagy,APG gene products,Neurogenesis,MAP |
| Function | Probably involved in formation of autophagosomal vacuoles (autophagosomes). |
| Molecular Weight | Theoretical: 14 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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