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Anti-CASP4 Polyclonal Antibody
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Catalog No. TMAB-00279
Alias TX protease, tx, Protease TX, Protease ICH-3, Protease ICH-2, Mih1/TX, ICH2, ICH 2 protease, ICH 2, ICERELII, ICEREL II, ICE(rel)II, ICE(rel) II, EC:3.4.22.64, Caspase-4 subunit p10, Caspase-4 subunit 2, Caspase4, Caspase-11, Caspase 4 apoptosis related cysteine peptidase, CASP4, CASP-11, CASP 4, Apoptotic cysteine protease Mih1/TX, Apoptosis related cysteine peptidase
Anti-CASP4 Polyclonal Antibody is a Rabbit antibody targeting CASP4. Anti-CASP4 Polyclonal Antibody can be used in WB.
Anti-CASP4 Polyclonal Antibody
Anti-CASP4 Polyclonal Antibody
😃Good
Catalog No. TMAB-00279Alias TX protease, tx, Protease TX, Protease ICH-3, Protease ICH-2, Mih1/TX, ICH2, ICH 2 protease, ICH 2, ICERELII, ICEREL II, ICE(rel)II, ICE(rel) II, EC:3.4.22.64, Caspase-4 subunit p10, Caspase-4 subunit 2, Caspase4, Caspase-11, Caspase 4 apoptosis related cysteine peptidase, CASP4, CASP-11, CASP 4, Apoptotic cysteine protease Mih1/TX, Apoptosis related cysteine peptidase
Anti-CASP4 Polyclonal Antibody is a Rabbit antibody targeting CASP4. Anti-CASP4 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CASP4 Polyclonal Antibody is a Rabbit antibody targeting CASP4. Anti-CASP4 Polyclonal Antibody can be used in WB. |
| Alias | TX protease, tx, Protease TX, Protease ICH-3, Protease ICH-2, Mih1/TX, ICH2, ICH 2 protease, ICH 2, ICERELII, ICEREL II, ICE(rel)II, ICE(rel) II, EC:3.4.22.64, Caspase-4 subunit p10, Caspase-4 subunit 2, Caspase4, Caspase-11, Caspase 4 apoptosis related cysteine peptidase, CASP4, CASP-11, CASP 4, Apoptotic cysteine protease Mih1/TX, Apoptosis related cysteine peptidase |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Mouse) |
| Verified Activity | Sample: Lane 1: Rat LympHnode tissue lysates Lane 2: Rat Lung tissue lysates Primary: Anti-CASP4 (TMAB-00279) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 10/43 kDa Observed band size: 47 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Research Background | Caspase 4 is a 377 amino acid protein (43 kDa) that belongs to the Ced3/ICE family of cystein proteases. Caspase 4 is an "upstream" caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits which have 67% homology to mature Caspase 1 over the equivalent coding sequences. Caspase 4 is capable of cleaving itself and the p30 Caspase 1 precursor, and of inducing apoptosis in transfected insect or COS cells. In high concentrations, it can also cleave the nuclear DNA enzyme PARP but the biological relevance of this cleavage is unclear. Caspase 4 mRNA is found in most tissues examined with the exception of the brain. Highest expression is found in spleen and lung, with moderate expression in heart and liver. Low expression is observed with skeletal muscle, kidney, and testis. |
| Immunogen | KLH conjugated synthetic peptide: mouse Caspase-4 subunit p10 |
| Antigen Species | Mouse |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Caspases |
| Molecular Weight | Theoretical: 10/43 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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