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Anti-CASP4 Polyclonal Antibody

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Catalog No. TMAB-00279
Alias TX protease, tx, Protease TX, Protease ICH-3, Protease ICH-2, Mih1/TX, ICH2, ICH 2 protease, ICH 2, ICERELII, ICEREL II, ICE(rel)II, ICE(rel) II, EC:3.4.22.64, Caspase-4 subunit p10, Caspase-4 subunit 2, Caspase4, Caspase-11, Caspase 4 apoptosis related cysteine peptidase, CASP4, CASP-11, CASP 4, Apoptotic cysteine protease Mih1/TX, Apoptosis related cysteine peptidase

Anti-CASP4 Polyclonal Antibody is a Rabbit antibody targeting CASP4. Anti-CASP4 Polyclonal Antibody can be used in WB.

Anti-CASP4 Polyclonal Antibody

Anti-CASP4 Polyclonal Antibody

😃Good
Catalog No. TMAB-00279Alias TX protease, tx, Protease TX, Protease ICH-3, Protease ICH-2, Mih1/TX, ICH2, ICH 2 protease, ICH 2, ICERELII, ICEREL II, ICE(rel)II, ICE(rel) II, EC:3.4.22.64, Caspase-4 subunit p10, Caspase-4 subunit 2, Caspase4, Caspase-11, Caspase 4 apoptosis related cysteine peptidase, CASP4, CASP-11, CASP 4, Apoptotic cysteine protease Mih1/TX, Apoptosis related cysteine peptidase
Anti-CASP4 Polyclonal Antibody is a Rabbit antibody targeting CASP4. Anti-CASP4 Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2217-10 days
100 μL$3737-10 days
200 μL$5277-10 days
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Product Introduction

Bioactivity
Description
Anti-CASP4 Polyclonal Antibody is a Rabbit antibody targeting CASP4. Anti-CASP4 Polyclonal Antibody can be used in WB.
AliasTX protease, tx, Protease TX, Protease ICH-3, Protease ICH-2, Mih1/TX, ICH2, ICH 2 protease, ICH 2, ICERELII, ICEREL II, ICE(rel)II, ICE(rel) II, EC:3.4.22.64, Caspase-4 subunit p10, Caspase-4 subunit 2, Caspase4, Caspase-11, Caspase 4 apoptosis related cysteine peptidase, CASP4, CASP-11, CASP 4, Apoptotic cysteine protease Mih1/TX, Apoptosis related cysteine peptidase
Ig Type
IgG
Reactivity
Rat (predicted:Mouse)
Verified Activity
Sample:
Lane 1: Rat LympHnode tissue lysates
Lane 2: Rat Lung tissue lysates
Primary: Anti-CASP4 (TMAB-00279) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 10/43 kDa
Observed band size: 47 kDa
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
FormulationPreservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
Research BackgroundCaspase 4 is a 377 amino acid protein (43 kDa) that belongs to the Ced3/ICE family of cystein proteases. Caspase 4 is an "upstream" caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits which have 67% homology to mature Caspase 1 over the equivalent coding sequences. Caspase 4 is capable of cleaving itself and the p30 Caspase 1 precursor, and of inducing apoptosis in transfected insect or COS cells. In high concentrations, it can also cleave the nuclear DNA enzyme PARP but the biological relevance of this cleavage is unclear. Caspase 4 mRNA is found in most tissues examined with the exception of the brain. Highest expression is found in spleen and lung, with moderate expression in heart and liver. Low expression is observed with skeletal muscle, kidney, and testis.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse Caspase-4 subunit p10
Antigen Species
Mouse
Gene ID
Uniprot ID
Biology Area
Caspases
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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