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Gadopentetate dimeglumine

Name: Gadopentetate dimeglumine
Brand: TargetMol
SKU: T4506
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T4506Cas No. 86050-77-3

Alias SH-L-451A, Meglumine gadopentetate, Gd-DTPA, Gadopentetic acid dimeglumine salt, Gadopentetic acid dimeglumine

Gadopentetate dimeglumine is used in magnetic resonance imaging (MRI) to allow blood vessels, organs and other non-bone tissues to be visualized more clearly.Gadopentetate dimeglumine induces atrophy of spermatogonia.

Gadopentetate dimeglumine

🥰Excellent

Purity: 99.62%

Catalog No. T4506Alias SH-L-451A, Meglumine gadopentetate, Gd-DTPA, Gadopentetic acid dimeglumine salt, Gadopentetic acid dimeglumineCas No. 86050-77-3

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	$34	In Stock	In Stock
200 mg	$58	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.62%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Gadopentetate dimeglumine is used in magnetic resonance imaging (MRI) to allow blood vessels, organs and other non-bone tissues to be visualized more clearly.Gadopentetate dimeglumine induces atrophy of spermatogonia.
In vivo	Interstitial MR lymphography with gadopentetate dimeglumine (Gd-DTPA) allows clear visualization of the lymphatic pathway in healthy mice, and no significant difference is found between the two agents. Their rapid kinetics limits the imaging timing window, however, facilitates repeated assessment in a single imaging session [1]. Direct visualization of spilled gastrointestinal gadopentetate dimeglumine helps discriminate ischemic from control rats in this model [2].
Synonyms	SH-L-451A, Meglumine gadopentetate, Gd-DTPA, Gadopentetic acid dimeglumine salt, Gadopentetic acid dimeglumine

Chemical Properties

Molecular Weight	938
Formula	C₁₄H₂₀GdN₃O₁₀.2C₇H₁₇NO₅
Cas No.	86050-77-3
Smiles	[Gd+3].CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)CN(CCN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O)CC([O-])=O
Relative Density.	no data available

Storage & Solubility Information

Storage

store under nitrogen | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 10 mg/mL (10.66 mM), Sonication is recommended.

DMSO: 250 mg/mL (266.52 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (3.52 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0661 mL	5.3305 mL	10.6610 mL	53.3049 mL
5 mM	0.2132 mL	1.0661 mL	2.1322 mL	10.6610 mL
10 mM	0.1066 mL	0.5330 mL	1.0661 mL	5.3305 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.0533 mL	0.2665 mL	0.5330 mL	2.6652 mL
50 mM	0.0213 mL	0.1066 mL	0.2132 mL	1.0661 mL
100 mM	0.0107 mL	0.0533 mL	0.1066 mL	0.5330 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc