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Quinupramine

🥰Excellent
Catalog No. T60707Cas No. 31721-17-2
Alias LM 208

Quinupramine (LM 208) is an orally available classical tricyclic antidepressant compound with a strong affinity for muscarinic and 5-HT receptors.Quinupramine crosses the central nervous system and can be used in the study of neurologic disorders.

Quinupramine

Quinupramine

🥰Excellent
Purity: 99.77%
Catalog No. T60707Alias LM 208Cas No. 31721-17-2
Quinupramine (LM 208) is an orally available classical tricyclic antidepressant compound with a strong affinity for muscarinic and 5-HT receptors.Quinupramine crosses the central nervous system and can be used in the study of neurologic disorders.
Pack SizePriceAvailabilityQuantity
1 mg$462In Stock
5 mg$1,070In Stock
25 mg$2,130In Stock
50 mg$2,780In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.77%
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Product Introduction

Bioactivity
Description
Quinupramine (LM 208) is an orally available classical tricyclic antidepressant compound with a strong affinity for muscarinic and 5-HT receptors.Quinupramine crosses the central nervous system and can be used in the study of neurologic disorders.
In vivo
In Sprague-Dawley rats (male, 220-270 g), Quinupramine (10 mg/kg; oral administration, twice daily for 10 days) caused down-regulation of serotonin S2 receptors in the frontal cortex of the rat but did not alter the binding populations of Q-adrenergic, muscarinic cholinergic, and α2-adrenergic receptors in the rat brain[2].
AliasLM 208
Chemical Properties
Molecular Weight304.43
FormulaC21H24N2
Cas No.31721-17-2
SmilesC=1C=CC2=C(C1)N(C=3C=CC=CC3CC2)C4CN5CCC4CC5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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