Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Quinupramine is an orally active antidepressant that shows antidepressant activity associated with the central serotonin system, but not with the β-adrenergic system. Quinupramine is able to penetrate into the CNS and affect some of neurotransmission processes [1] [2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 462.00 | |
5 mg | In stock | $ 1,070.00 | |
25 mg | In stock | $ 2,130.00 | |
50 mg | In stock | $ 2,780.00 |
Description | Quinupramine is an orally active antidepressant that shows antidepressant activity associated with the central serotonin system, but not with the β-adrenergic system. Quinupramine is able to penetrate into the CNS and affect some of neurotransmission processes [1] [2]. |
In vivo | Quinupramine, administered orally at a dosage of 10 mg/kg twice daily for 10 days to male Sprague-Dawley rats weighing 220-270 g, leads to a down-regulation of serotonin S2 receptors in the rat's frontal cortex without affecting the binding populations of β-adrenergic, muscarinic cholinergic, and α2-adrenergic receptors in the brain. Additionally, a Quinupramine-EVA matrix incorporating a permeation enhancer shows potential as an efficacious transdermal delivery system for achieving sustained plasma concentrations. |
Molecular Weight | 304.43 |
Formula | C21H24N2 |
CAS No. | 31721-17-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Quinupramine 31721-17-2 inhibitor inhibit