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Anti-Phospho-STAT5A (Y694) Antibody (5T706)
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Catalog No. TMAC-03277
Anti-Phospho-STAT5A (Y694) Antibody (5T706) is a Rabbit antibody targeting Phospho-STAT5A (Y694). Anti-Phospho-STAT5A (Y694) Antibody (5T706) can be used in WB,IHC.
Anti-Phospho-STAT5A (Y694) Antibody (5T706)
Anti-Phospho-STAT5A (Y694) Antibody (5T706)
😃Good
Catalog No. TMAC-03277
Anti-Phospho-STAT5A (Y694) Antibody (5T706) is a Rabbit antibody targeting Phospho-STAT5A (Y694). Anti-Phospho-STAT5A (Y694) Antibody (5T706) can be used in WB,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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| Description | Anti-Phospho-STAT5A (Y694) Antibody (5T706) is a Rabbit antibody targeting Phospho-STAT5A (Y694). Anti-Phospho-STAT5A (Y694) Antibody (5T706) can be used in WB,IHC. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Stat5 (Signal Transducers and Activators of Transcription 5) is important in regulating T cell functions involving the receptors for Interleukin-2 (IL-2). IL-2 stimulates the rapid phosphorylation of both serine and tyrosine residues of Stat5a and Stat5b in human T lymphocytes and in several IL-2-responsive lymphocytic cell lines. IL-2 differentially induces serine phosphorylation of Stat5a and Stat5b on Ser726 and Ser731, respectively. Stat5b is preferentially phosphorylated and displays more protracted serine phosphorylation kinetics than Stat5a. Both the acid-rich region and the COOH terminus of IL-2Rb can independently mediate IL-2-induced Stat 5a/b serine phosphorylation, suggesting that Stat5a/b serine phosphorylation occurs at a postreceptor level. Stat5a is phosphorylated on Tyr694 in a prolactin-sensitive manner, whereas serine phosphorylation is constitutive. Activation of Stat5 by IL-2 may help govern the biological effects of IL-2 during the immune response. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human Stat5 around the phosphorylation site of Tyr694 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 90 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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