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Glucocorticoid receptor modulator 1 is a potent, orally active, non-steroidal selective glucocorticoid receptor modulator, exhibiting IC50 values of 9 nM and 130 nM against NF-κB and AP-1, respectively. It effectively reduces the expression of inflammatory factors such as IL-6, IL-1β, and TNF-α, and alleviates dermatitis in mice.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $112 | In Stock | |
5 mg | $277 | In Stock | |
10 mg | $443 | In Stock | |
25 mg | $887 | In Stock | |
50 mg | $1,350 | In Stock | |
100 mg | $2,150 | In Stock | |
1 mL x 10 mM (in DMSO) | $288 | In Stock |
Description | Glucocorticoid receptor modulator 1 is a potent, orally active, non-steroidal selective glucocorticoid receptor modulator, exhibiting IC50 values of 9 nM and 130 nM against NF-κB and AP-1, respectively. It effectively reduces the expression of inflammatory factors such as IL-6, IL-1β, and TNF-α, and alleviates dermatitis in mice. |
Molecular Weight | 470.97 |
Formula | C24H23ClN2O4S |
Cas No. | 2868357-11-1 |
Smiles | C(=O)(N1C=2C(=CC(NS(=O)(=O)C3=C(OC)C=C(C)C(Cl)=C3)=CC2)CCC1)C4=CC=CC=C4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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