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Anti-FKBP12 Antibody (2Z412)
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Catalog No. TMAC-01489
Alias PPIASE, PKCI2, PKC12, FKBP-1A, FKBP-12, FKBP12, FKBP1, FK506 binding protein 1A
Anti-FKBP12 Antibody (2Z412) is a Rabbit antibody targeting FKBP12. Anti-FKBP12 Antibody (2Z412) can be used in WB,ICC/IF.
Anti-FKBP12 Antibody (2Z412)
Anti-FKBP12 Antibody (2Z412)
😃Good
Catalog No. TMAC-01489Alias PPIASE, PKCI2, PKC12, FKBP-1A, FKBP-12, FKBP12, FKBP1, FK506 binding protein 1A
Anti-FKBP12 Antibody (2Z412) is a Rabbit antibody targeting FKBP12. Anti-FKBP12 Antibody (2Z412) can be used in WB,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-FKBP12 Antibody (2Z412) is a Rabbit antibody targeting FKBP12. Anti-FKBP12 Antibody (2Z412) can be used in WB,ICC/IF. |
| Synonyms | PPIASE, PKCI2, PKC12, FKBP-1A, FKBP-12, FKBP12, FKBP1, FK506 binding protein 1A |
| Ig Type | IgG |
| Clone | 2Z412 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of FKBP12 on different cells lysates using anti-FKBP12 antibody at 1/500 dilution. Positive control: Line 1: SH-SY5Y, Line 2:V937. 2. ICC staining FKBP12 in A431 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining FKBP12 in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining FKBP12 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:500-1000; ICC/IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases which bind to and mediate the effects of immunosuppressive drugs such as Cyclosporin, FK506 and Rapamycin. FKBP12.6, also known as FK506-binding protein 1B, is a 108 amino acid immunophilin belonging to the FKBP-type PPIase family. Subcellularly localized to the cytoplasm, FKBP12.6 binds to RyR in cardiac muscle sarcoplasmic reticulum and possibly plays a unique physiological role in excitation-contraction coupling in cardiac muscle. FKBP12.6 also catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Ubiquitously expressed, FKBP12.6 is found at highest levels in brain and thymus. FKBP12.6 is expressed as two isoforms produced by alternative splicing. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 12 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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