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4-Desmethoxy Omeprazole

🥰Excellent
Catalog No. T10138Cas No. 110374-16-8

4-Desmethoxy Omeprazole, the active metabolite of Omeprazole, acts as a proton pump inhibitor (PPI) and demonstrates competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM.

4-Desmethoxy Omeprazole

4-Desmethoxy Omeprazole

🥰Excellent
Purity: 98.96%
Catalog No. T10138Cas No. 110374-16-8
4-Desmethoxy Omeprazole, the active metabolite of Omeprazole, acts as a proton pump inhibitor (PPI) and demonstrates competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$55In StockIn Stock
5 mg$127In StockIn Stock
10 mg$190In StockIn Stock
25 mg$313In StockIn Stock
50 mg$441In StockIn Stock
100 mg$596-In Stock
200 mg$825-In Stock
1 mL x 10 mM (in DMSO)$125In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.96%
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Product Introduction

Bioactivity
Description
4-Desmethoxy Omeprazole, the active metabolite of Omeprazole, acts as a proton pump inhibitor (PPI) and demonstrates competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM.
Chemical Properties
Molecular Weight315.39
FormulaC16H17N3O2S
Cas No.110374-16-8
SmilesCOc1ccc2[nH]c(nc2c1)S(=O)Cc1ncc(C)cc1C
Relative Density.1.37 g/cm3 at 20℃
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (87.19 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1707 mL15.8534 mL31.7068 mL158.5339 mL
5 mM0.6341 mL3.1707 mL6.3414 mL31.7068 mL
10 mM0.3171 mL1.5853 mL3.1707 mL15.8534 mL
20 mM0.1585 mL0.7927 mL1.5853 mL7.9267 mL
50 mM0.0634 mL0.3171 mL0.6341 mL3.1707 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

InhibitorinhibitDrugMetaboliteDrug Metabolite4-Desmethoxy Omeprazole4Desmethoxy Omeprazole4 Desmethoxy Omeprazole
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