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pep2-SVKI

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Catalog No. TP1944Cas No. 328944-75-8

Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit. Disrupts binding of GluA2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and protein interacting with C kinase (PICK1). Increases amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD).

pep2-SVKI
Other Forms of pep2-SVKI:
pep2-SVKI acetateTP1944L1
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pep2-SVKI

😃Good
Catalog No. TP1944Cas No. 328944-75-8
Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit. Disrupts binding of GluA2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and protein interacting with C kinase (PICK1). Increases amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD).
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2 mg$166InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Description
Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit. Disrupts binding of GluA2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and protein interacting with C kinase (PICK1). Increases amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD).
Chemical Properties
Molecular Weight1284.47
FormulaC60H93N13O18
Cas No.328944-75-8
Smiles[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)N)=O)CC(N)=O)=O)[C@@H](C)C)=O)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CCCCN)=O)C(C)C)=O)CO)=O)CCC(O)=O)=O)[C@H](CC)C)=O)=O
Relative Density.1.286 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 1 mg/mL (0.78 mM), Sonication is recommended.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

pep2-SVKIpep-2-SVKIpep2SVKIpep2 SVKI
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